Aldevron LLC
Aldevron is a leader in advancing biological science by providing high-quality plasmid DNA, proteins, enzymes, and other biologicals. They offer comprehensive development and manufacturing services, supporting groundbreaking research and therapeutic projects in gene therapy, gene-modified cell therapy, gene editing, RNA vaccines & therapeutics, and more. As part of Danaher, they leverage extensive expertise and innovative solutions to help clients accelerate their scientific and medical breakthroughs.
Industries
Nr. of Employees
medium (51-250)
Aldevron LLC
Fargo, North Dakota, United States, North America
Products
CRISPR nucleases (research and clinical grades)
High-fidelity and wild-type nuclease reagents supplied at research and clinical manufacturing grades to support gene editing workflows.
In vitro transcription and capping enzymes
Enzymes and related reagents to enable IVT workflows and RNA capping for mRNA production workflows.
Viral vector plasmids (AAV & lentiviral)
Expression and helper plasmids designed to support production of high-titer AAV and lentiviral vectors for research and clinical manufacturing.
Cloning backbones and small plasmid vectors
Inventory of empty cloning backbones and small-format plasmid vectors that can be modified for customer applications; offered royalty-free in many formats.
DNA/RNA reporter constructs
Reporter constructs expressing fluorescent proteins and controls for transfection assessment and assay development.
CRISPR nucleases (research and clinical grades)
High-fidelity and wild-type nuclease reagents supplied at research and clinical manufacturing grades to support gene editing workflows.
In vitro transcription and capping enzymes
Enzymes and related reagents to enable IVT workflows and RNA capping for mRNA production workflows.
Viral vector plasmids (AAV & lentiviral)
Expression and helper plasmids designed to support production of high-titer AAV and lentiviral vectors for research and clinical manufacturing.
Cloning backbones and small plasmid vectors
Inventory of empty cloning backbones and small-format plasmid vectors that can be modified for customer applications; offered royalty-free in many formats.
DNA/RNA reporter constructs
Reporter constructs expressing fluorescent proteins and controls for transfection assessment and assay development.
Services
Custom manufacturing for plasmid DNA, RNA, proteins and enzymes
Contract development and manufacture of plasmid DNA, mRNA, proteins and enzymes at research through cGMP quality levels, including process development and scale-up.
mRNA drug product development with LNP encapsulation and sterile fill/finish
End-to-end services from RNA design and IVT through LNP formulation, encapsulation, sterile fill/finish and analytics for clinical drug product supply.
Process development and scale-up services
Process optimization, technology transfer, and scale-up support for plasmid, RNA, protein and viral product manufacturing to support clinical and commercial timelines.
Analytical testing and quality control services
Method development, release testing, and analytical characterization to support product development and regulatory submissions.
Regulatory and GMP readiness support
Support for GMP compliance, regulatory inspections, and quality system implementation to prepare facilities and products for clinical trial supply.
Catalog reagent and vector supply
Off-the-shelf reagents and molecular biology products available in research and GMP-capable formats to accelerate discovery and translational programs.
Custom manufacturing for plasmid DNA, RNA, proteins and enzymes
Contract development and manufacture of plasmid DNA, mRNA, proteins and enzymes at research through cGMP quality levels, including process development and scale-up.
mRNA drug product development with LNP encapsulation and sterile fill/finish
End-to-end services from RNA design and IVT through LNP formulation, encapsulation, sterile fill/finish and analytics for clinical drug product supply.
Process development and scale-up services
Process optimization, technology transfer, and scale-up support for plasmid, RNA, protein and viral product manufacturing to support clinical and commercial timelines.
Analytical testing and quality control services
Method development, release testing, and analytical characterization to support product development and regulatory submissions.
Regulatory and GMP readiness support
Support for GMP compliance, regulatory inspections, and quality system implementation to prepare facilities and products for clinical trial supply.
Catalog reagent and vector supply
Off-the-shelf reagents and molecular biology products available in research and GMP-capable formats to accelerate discovery and translational programs.
Expertise Areas
- Plasmid DNA manufacturing
- mRNA drug substance and LNP formulation
- Viral vector plasmid production
- Protein and enzyme production for research and diagnostics
Key Technologies
- Plasmid DNA production
- In vitro transcription (IVT)
- Lipid nanoparticle (LNP) encapsulation
- mRNA manufacturing