Invenra, Inc.


Invenra is a biotechnology company dedicated to advancing therapeutic antibody discovery and development. They focus on innovative platforms such as the B-Body® Bispecific Platform and the T-Body™ Trispecific Antibody Platform to create high-yield, stable, and effective bispecific and trispecific antibodies. Their mission is to enable the discovery of novel therapies across various disease categories, with a strong emphasis on oncology. Invenra offers flexible solutions including rapid discovery services, collaborative development partnerships, and a comprehensive pipeline of antibody candidates aimed at improving patient health.

Industries

biotechnology
life-science
medical
pharmaceutical

Nr. of Employees

small (1-50)

Invenra, Inc.

Madison, Wisconsin, United States, North America


Products

Bispecific antibody engineering platform optimized for high yield and CMC compatibility

A human IgG-like platform architecture engineered for high expression yield, correct heterodimer assembly, single-step affinity purification for discovery, and compatibility with conventional CMC downstream processes and subcutaneous formulation requirements.

Trispecific antibody engineering platform for multi‑antigen engagement

An antibody architecture engineered to integrate three antigen-binding arms into an IgG-like structure using domain engineering to enable simultaneous binding to three distinct targets and to facilitate high expression, assembly, and purification.


Services

Rapid multispecific discovery service

Parallel functional screening of large combinatorial bispecific panels to generate lead panels on a 2–4 month timeline; includes downstream expression in multiple formats for follow-up testing.

Rapid small-scale expression and two-step purification service

Research-scale antibody expression services producing two-step purified samples (small volumes) within accelerated timelines to support early-stage evaluation.

End-to-end collaborative development services

Strategic, integrated partnerships offering custom antigen design, assay development, biological analysis, expression in multiple formats, and support for large-scale preclinical studies.

Expertise Areas

  • Multispecific antibody engineering
  • Antibody discovery and high-throughput functional screening
  • Mammalian cell expression and cell line development
  • Downstream purification and CMC development
  • Show More (4)

Key Technologies

  • CHO and HEK mammalian expression systems
  • Transient and stable cell line expression
  • Fed-batch and perfusion bioreactors
  • Protein A and ion-exchange chromatography
  • Show More (9)

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