Adipo Therapeutic
Adipo Therapeutics is dedicated to advancing obesity treatment by harnessing the power of brown fat to increase energy expenditure. Their innovative approach involves developing therapies that convert white fat into brown fat using Notch-inhibiting nanoparticles, aiming to promote weight loss and metabolic health without the need for calorie restriction.
Industries
Nr. of Employees
small (1-50)
Adipo Therapeutic
Products
Notch-inhibiting PLGA nanoparticle therapy (lead candidate)
A preclinical injectable therapy comprising biodegradable polymer nanoparticles formulated to deliver a Notch pathway inhibitor locally to subcutaneous white adipose tissue to induce browning and increased energy expenditure.
Notch-inhibiting PLGA nanoparticle therapy (lead candidate)
A preclinical injectable therapy comprising biodegradable polymer nanoparticles formulated to deliver a Notch pathway inhibitor locally to subcutaneous white adipose tissue to induce browning and increased energy expenditure.
Services
Execution of in vitro and ex vivo assays using human adipose tissue and cultured adipocytes to evaluate browning biomarkers and mechanistic translation of candidate therapies.
Execution of in vitro and ex vivo assays using human adipose tissue and cultured adipocytes to evaluate browning biomarkers and mechanistic translation of candidate therapies.
Expertise Areas
- Adipose tissue biology and adipocyte browning
- Nanoparticle drug delivery
- Biomaterials engineering
- Preclinical pharmacology and toxicology
Key Technologies
- Biodegradable PLGA nanoparticle carriers
- Notch signaling pathway inhibition
- Subcutaneous depot-forming injectable delivery
- Controlled intracellular release
News & Updates
Adipo Therapeutics demonstrated browning of human white adipose tissue in ex-vivo study at the 2024 Annual Meeting.
An article discussing the potential of brown fat in obesity treatment.
Research on brown adipose tissue and its impact on cardiovascular health.
An article about brown adipose tissue and its health benefits.
Study on brown adipose tissue presence in healthy adults.
Demonstrated browning of human white adipose tissue in ex-vivo study.
Adipo Therapeutics demonstrated browning of human white adipose tissue in ex-vivo study at the 2024 Annual Meeting.
An article discussing the potential of brown fat in obesity treatment.
Research on brown adipose tissue and its impact on cardiovascular health.
An article about brown adipose tissue and its health benefits.
Study on brown adipose tissue presence in healthy adults.
Demonstrated browning of human white adipose tissue in ex-vivo study.