Psychological and Cognitive Health and Performance

This capability integrates validated biomarkers, wearable neurophysiologic sensors, standardized neurocognitive assessment, and evidence-based countermeasures (pharmacologic, behavioral, neuromodulation) to diagnose, monitor, mitigate, and restore cognitive and psychological health in operational environments including TBI, PTSD, sleep disruption, and performance under stress.

Technical Challenges

  • Lack of objective, field-deployable biomarkers to differentiate mTBI, neuroinflammation, PTSD, and metabolic effects of sleep loss.

  • Reliable, artifact-resistant physiological monitoring in high-motion, noisy, and electromagnetic environments.

  • Rapid neurocognitive assessment and longitudinal tracking that are validated for diverse operational populations and multilingual cohorts.

  • Delivering scalable, evidence-based interventions (behavioral, pharmacologic, neuromodulation) that are effective in austere, prolonged-care scenarios.

Emerging Opportunities

  • Portable point-of-care assays and biosignatures (blood, saliva, proteomic/metabolomic) validated for acute brain injury and neuroinflammation.

  • Robust wearable EEG/physiologic systems and algorithms validated for noisy battlefield conditions and prolonged use.

  • Validated digital biomarkers and decision-support tools for remote triage, prognostication, and return-to-duty determinations.

  • Field-adapted rehabilitation and resilience platforms that deliver measurable cognitive recovery and retention under operational constraints.

Current and Emerging Technologies in Psychological and Cognitive Health and Performance

Wearable biosensors and physiological monitoring

Continuous heart rate variability, actigraphy, sleep staging, and peripheral markers that correlate with stress, fatigue, and recovery to inform readiness and early intervention.

Portable EEG and neurophysiologic platforms

Low-channel, motion-tolerant EEG and quantitative EEG analytics for concussion detection, cognitive workload assessment, and monitoring treatment response in-field.

Blood- and biofluid-based biomarkers and rapid assays

Assays for axonal injury, neuroinflammation, and stress-response proteins adapted to point-of-care platforms for triage and prognostication.

Digital neurocognitive assessment and AI analytics

Validated mobile cognitive batteries, passive digital biomarkers, and machine-learning models that detect subtle deficits and predict functional outcomes.

Interventions: neuromodulation and therapeutics

Transcranial electrical/magnetic stimulation, targeted pharmacotherapies, and modular behavioral programs optimized for rapid deployment and remote supervision.

Importance to Military Medicine

Preserve force readiness and decision-making

Cognitive and psychological integrity underpins tactical performance, command decision-making, and unit cohesion.

Improve outcomes in combat casualty and prolonged field care

Early detection and intervention for TBI, neuroinflammation, and stress disorders reduces secondary injury, disability, and evacuation burden.

Enable austere and distributed care

Field-deployable diagnostics and telemedicine tools extend neuropsychological care when specialist support is delayed or unavailable.

Reduce long-term disability and preserve reintegration

Timely, validated therapies mitigate chronic PTSD, cognitive impairment, and psychiatric comorbidity, improving long-term health and retention.

Alignment with the MTEC Mission

Accelerates transition of military-relevant neurotechnology from prototype to operational use through consortium-enabled partnerships and rapid clinical evaluation.

Fosters multidisciplinary solutions spanning diagnostics, therapeutics, and digital health consistent with MTEC’s mission to prioritize Warfighter health.

Enables dual-use impact by emphasizing civilian benefit—emergency medicine, sports concussion, and mental health care—alongside DoD priorities.

Leverages DoD test beds, operational requirements, and accelerated acquisition pathways central to MTEC’s consortium model.

Dual-Use (Military + Civilian) Applications

Civilian emergency and occupational health: rapid TBI and stress detection for EMS, first responders, and high-risk industries.

Sports medicine and concussion management: validated wearables and biomarkers to guide return-to-play and rehabilitation.

Tele-mental health and digital therapeutics: scalable behavioral and cognitive training platforms for remote populations.

Clinical research and public health: biomarkers and analytics to improve outcomes for PTSD, neurodegeneration, and sleep disorders in civilian care.

Explore MTEC Members with Psychological and Cognitive Health and Performance Capabilities

MTEC members bring multidisciplinary expertise—biomarker science, neuroengineering, clinical neurology/psychiatry, and operational medicine—plus access to DoD-relevant test beds and expedited pathways for validation. Explore member profiles to identify partners with capabilities in wearable sensing, rapid assays, digital therapeutics, and clinical trials infrastructure.

178 Members with Psychological and Cognitive Health and Performance capabilities.

Member
The University of Texas System

The University of Texas System is a leading public university system in the United States, dedicated to improving lives through education, health care, and research. With over 256,000 students enrolled across 14 institutions, the UT System is committed to providing affordable access to higher education and producing a skilled workforce to drive Texas's economy.

Member
SIMETRI

SIMETRI is a woman-and-minority owned small business based in Winter Park, Florida, specializing in modeling, simulation, and training technologies. Founded in 2009, the company focuses on delivering innovative products and services that enhance the human experience and improve client outcomes through advanced training and program management analysis.

Member
IQVIA

IQVIA is a global leader in advanced analytics, technology solutions, and clinical research services for the life sciences industry. With a mission to accelerate innovation for a healthier world and a vision to power smarter healthcare for everyone, everywhere, IQVIA leverages unparalleled data, transformative technology, and deep healthcare expertise to drive better patient outcomes. Operating in over 100 countries with approximately 88,000 employees, IQVIA supports pharmaceutical, biotech, medtech, public health, and government organizations with a comprehensive portfolio of services and solutions. The company is recognized for its Connected Intelligence™, healthcare-grade AI, and commitment to sustainability, innovation, and evidence-based insights that shape the future of healthcare globally. IQVIA is also dedicated to reducing health inequities and driving sustainable change through innovation, collaboration, and data-driven solutions, partnering with organizations worldwide to address complex healthcare challenges.

Member
Georgia Southern University

Georgia Southern University is a vibrant institution with over 26,100 students across three campuses in Statesboro, Savannah, and Hinesville. The university offers 132 degree programs at the associate, bachelor’s, master’s, and doctorate levels, emphasizing student success, community impact, and research excellence. With a commitment to inclusivity and engagement, Georgia Southern fosters a supportive environment for diverse learners, including military-affiliated and adult students. The university is dedicated to transforming lives through education and community engagement, aligning its programs with regional needs. Additionally, Georgia Southern provides accelerated pathways for students to fast-track their master's degrees, enhancing educational opportunities. The university also emphasizes career readiness and public impact research, preparing students for successful careers and contributing to community development.

Member
Vivamed Inc.

Vivamed focuses on the development of novel diagnostic and therapeutic medical devices.

Member
Institutes for Behavior Resources, Inc.

Founded in 1960 by Dr. Joseph V. Brady, the Institutes for Behavior Resources, Inc. (IBR) is a nonprofit organization dedicated to enhancing the growth of behavioral sciences and their application to human affairs through research, clinical services, and educational initiatives. IBR focuses on addressing social challenges through innovative research and comprehensive health services.

Member
MyndBlue

MyndBlue: Redefining Mental Health Care with Bold Innovation Step into the future of mental readiness with MyndBlue, a visionary MedTech pioneer revolutionizing how mental health is diagnosed and treated. We blend groundbreaking physiological insights with the brilliance of advanced AI to deliver precision-driven, personalized clinical solutions that set a new standard in care. At MyndBlue, we’re on a mission to transform lives of by equipping physicians with dynamic, real-time tools to identify and predict conditions like Major Depressive Disorder (MDD) and Post-Traumatic Stress Disorder (PTSD). Our cutting-edge technology empowers earlier, smarter interventions—unlocking better outcomes and illuminating a hopeful path forward for mental health.

Member
Humanetics Corporation

Humanetics Corporation is a clinical-stage pharmaceutical company based in Minneapolis, Minnesota, focused on developing and commercializing products to enhance human health and wellbeing. Founded in 1988, the company specializes in radiation modulators, adjunctive oncology therapies, and pulmonary protective therapies, particularly for COVID-19. Humanetics is known for its lead drug candidate, BIO 300, which is being developed as a radioprotectant for military and civilian use, as well as a treatment to improve outcomes in cancer patients receiving radiotherapy. The company is actively engaged in research programs for non-small cell lung cancer, prostate cancer, and head and neck cancers.

Member
Aware Custom Biometric Wearables

Aware Custom Biometric Wearables, is a leading innovator in cutting-edge in-ear technology, specializing in superior custom hearing protection solutions and biometric hearables. Our groundbreaking in-ear solutions feature enhanced hearing capabilities, continuous monitoring, and the collection of medical-grade biometric data, all designed to enhance human performance and safeguard lives. Our commitment to innovation is reflected in our meticulously crafted in-ear devices. Thanks to our patented 3D Ear Scanner technology, we provide a custom fit tailored to the unique shape of each individual's ear which optimizes the performance of sensors. Aware is transforming the ear into a dynamic platform for health and human performance by collecting medical-grade data, delivering actionable AI-driven insights, and enabling precision therapeutics within devices we wear in our everyday lives. Our technology serves a diverse range of sectors within healthcare, military, and industrial. Proudly U.S.-based, offices in Atlanta, GA and San Diego, CA. www.AwareCBW.com.

Member
STAT Therapeutics

STAT Therapeutics is focused on developing a drug- device combination for easy, rapid administration of intramuscular, life-saving medications by users in any setting, aiming to improve access and usability for acute emergency treatments such as pain, anaphylaxis, and seizures.

Member
CRI Genetics

CRI Genetics, part of the Cellular Research Institute, aims to unlock complex genetic information and present it in an engaging and useful manner. Their mission is to enhance human life and advance the understanding of the human genome through consumer genetic reports and active participation in scientific research. They believe genetic analysis is the future of medicine and are committed to solving complex medical problems. The company ensures the privacy and security of customer data, offering an 8-week efficiency guarantee for delivering genetic reports.

Member
Pulsara

Pulsara is a purpose-driven healthcare technology company focused on improving the lives of patients and caregivers through innovative, real-time communication and collaboration. Their telehealth platform connects clinicians, EMS, hospitals, and emergency management teams on a single patient channel, enabling dynamic, scalable, and secure care coordination for any illness or injury. Pulsara's evidence-based solutions are designed to reduce treatment times, lower costs, and enhance experiences for both patients and providers. The company is recognized for its customer-first values, award-winning support, and commitment to privacy, security, and interoperability.

Member
The University of Texas at San Antonio

The University of Texas at San Antonio (UTSA) is dedicated to the advancement of knowledge through research, teaching, and community engagement. As a premier public research university, UTSA embraces multicultural traditions and serves as a catalyst for socioeconomic development, providing access to educational excellence and preparing citizen leaders for the global environment.

Member
Auburn University

Auburn University Research & Economic Development is dedicated to advancing research and economic growth through a collaborative effort among its various colleges and departments. The organization focuses on fostering innovation, supporting faculty and student research, and facilitating partnerships with industry and government to address societal challenges and enhance the quality of life. Recent initiatives include the launch of the Team Science Series to promote interdisciplinary collaboration and the development of the Gulf Coast Engineering Research Station to address coastal environmental challenges.

Member
University of Arkansas

The Institute for Integrative & Innovative Research (I3R) at the University of Arkansas is dedicated to pioneering solutions to complex societal challenges through convergence research. With a mission to advance research excellence and stimulate economic development, I3R focuses on deploying innovations at scale through collaboration across various sectors, including academia, industry, and government.

Member
The University of Texas Medical Branch at Galveston

UTMB is dedicated to supporting research, education, and scholarly endeavors, with a focus on creating the future of healthcare through innovative research and community engagement.

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Projects

Technology Showcase

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Arizona State University

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