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Explore MTEC's network of innovators, investors, and research organizations—along with patents and funding opportunities—advancing medical technologies for military and civilian health.

Showing 18 Patents
Device and methods of using device for detection of hyperammonemia

24-04-2018 • US-9952199-B2

AYYUB, OMAR BILAL • BEHRENS, ADAM MICHAEL • KOFINAS, PETER • SUMMAR, MARSHALL LYNN • CABRERA-LUQUE, JUAN MANUEL • CUNNINGHAM, GARY • SIMEONOV, ANTON • MARUGAN, JUAN

Childrens National Medical Center Inc • University of Maryland College Park • US Department of Health and Human Services

Inhibitors of the USP1/UAF1 deubiquitinase complex and uses thereof

31-10-2017 • US-9802904-B2

MALONEY, DAVID J. • ROSENTHAL, ANDREW S. • JADHAV, AJIT • DEXHEIMER, THOMAS S. • SIMEONOV, ANTON • ZHUANG, ZHIHAO • LIANG, QIN • LUCI, DIANE K.

University of Delaware • US Department of Health and Human Services

Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

13-02-2024 • US-11897845-B2

MALONEY, DAVID J. • WATERSON, ALEX GREGORY • BANTUKALLU, GANESH RAI • BRIMACOMBE, KYLE RYAN • CHRISTOV, PLAMEN • DANG, CHI V. • DARLEY-USMAR, VICTOR • HU, XIN • JADHAV, AJIT • JANA, SOMNATH • KIM, KWANGHO • KOUZNETSOVA, JENNIFER L. • MOORE, WILLIAM J. • MOTT, BRYAN T. • NECKERS, LEONARD M. • SIMEONOV, ANTON • SULIKOWSKI, GARY ALLEN • URBAN, DANIEL JASON • YANG, SHYH MING

UAB Research Foundation • University of Pennsylvania Penn • Vanderbilt University • US Department of Health and Human Services

Substituted quinoline analogs as aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors

24-10-2023 • US-11795177-B2

YANG, SHYH MING • MALONEY, DAVID J. • MARTINEZ, NATALIA • YASGAR, ADAM • SIMEONOV, ANTON

US Department of Health and Human Services

Substituted quinoline analogs as aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors

22-11-2022 • US-11505559-B2

YANG, SHYH MING • MALONEY, DAVID J. • MARTINEZ, NATALIA • YASGAR, ADAM • SIMEONOV, ANTON • VASILIOU, VASILIS

Yale University • Office of Technology Transfer

4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

15-03-2022 • US-11274077-B2

MALONEY, DAVID J. • LUCI, DIANE K. • JADHAV, AJIT • HOLMAN, THEODORE • NADLER, JERRY L. • HOLINSTAT, MICHAEL • TAYLOR-FISHWICK, DAVID • SIMEONOV, ANTON • YASGAR, ADAM • MCKENZIE, STEVEN

United States, Department Of Health • Thomas Jefferson University • Eastern Virginia Medical School • University of California Santa Barbara UCSB • University of California Santa Cruz • US Department of Health and Human Services

Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

15-02-2022 • US-11247971-B2

MALONEY, DAVID J. • WATERSON, ALEX GREGORY • BANTUKALLU, GANESH RAI • BRIMACOMBE, KYLE RYAN • CHRISTOV, PLAMEN • DANG, CHI V. • DARLEY-USMAR, VICTOR • HU, XIN • JADHAV, AJIT • JANA, SOMNATH • KIM, KWANGHO • KOUZNETSOVA, JENNIFER L. • MOORE, WILLIAM J. • MOTT, BRYAN T. • NECKERS, LEONARD M. • SIMEONOV, ANTON • SULIKOWSKI, GARY ALLEN • URBAN, DANIEL JASON • YANG, SHYH MING

UAB Research Foundation • University of Pennsylvania Penn • Vanderbilt University • US Department of Health and Human Services

Pyridazinones and their use in the treatment of cancer

07-09-2021 • US-11110089-B2

ARNÉR, ELIAS SET JENÖ • STAFFORD, WILLIAM CHESTER • COUSSENS, NATHAN PATRICK • LUCI, DIANE KAREN • MALONEY, DAVID JOSEPH • SIMEONOV, ANTON • JADHAV, AJIT • DEXHEIMER, THOMAS S.

Elias Set Jeno Arner • US Department of Health and Human Services

Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

30-03-2021 • US-10961200-B2

MALONEY, DAVID J. • WATERSON, ALEX GREGORY • BANTUKALLU, GANESH RAI • BRIMACOMBE, KYLE RYAN • CHRISTOV, PLAMEN • DANG, CHI V. • DARLEY-USMAR, VICTOR • HU, XIN • JADHAV, AJIT • JANA, SOMNATH • KIM, KWANGHO • KOUZNETSOVA, JENNIFER L. • MOORE, WILLIAM J. • MOTT, BRYAN T. • NECKERS, LEONARD M. • SIMEONOV, ANTON • SULIKOWSKI, GARY ALLEN • URBAN, DANIEL JASON • YANG, SHYH MING

UAB Research Foundation • University of Pennsylvania Penn • Vanderbilt University • US Department of Health and Human Services

1 H-pyrazol-1-yl-thiazoles as inhibitors of lactate dehydrogenase and methods of use thereof

23-03-2021 • US-10954228-B2

MALONEY, DAVID J. • WATERSON, ALEX GREGORY • BANTUKALLU, GANESHA RAI • BRIMACOMBE, KYLE RYAN • CHRISTOV, PLAMEN • DANG, CHI V. • DARLEY-USMAR, VICTOR M. • HALL, MATTHEW • HU, XIN • JADHAV, AJIT • JANA, SOMNATH • KIM, KWANGHO • MOORE, WILLIAM J. • MOTT, BRYAN T. • NECKERS, LEONARD M. • SIMEONOV, ANTON • SULIKOWSKI, GARY ALLEN • URBAN, DANIEL JASON • YANG, SHYH MING

UAB Research Foundation • University of Pennsylvania Penn • Vanderbilt University • National Institutes of Health NIH

Thiazole derivatives useful as mutant IDH1 inhibitors for treating cancer

17-11-2020 • US-10836759-B2

BOXER, MATTHEW BRIAN • WANG, XIAODONG • BRIMACOMBE, KYLE RYAN • DAVIS, MINDY IRENE EMILY • FANG, YUHONG • HALL, MATTHEW • JADHAV, AJIT • KARAVADHI, SURENDRA • LIU, LI • MARTINEZ, NATALIA • MCIVER, ANDREW LOUIS • PRAGANI, RAJAN • ROHDE, JASON MATTHEW • SIMEONOV, ANTON • ZHAO, WEI • SHEN, MIN

University of North Carolina at Chapel Hill • US Department of Health and Human Services

4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

25-08-2020 • US-10752581-B2

MALONEY, DAVID J. • LUCI, DIANE K. • JADHAV, AJIT • HOLMAN, THEODORE • NADLER, JERRY L. • HOLINSTAT, MICHAEL • TAYLOR-FISHWICK, DAVID • SIMEONOV, ANTON • YASGAR, ADAM • MCKENZIE, STEVEN

United States, Department Of Health • Thomas Jefferson University • Eastern Virginia Medical School • University of California Santa Barbara UCSB • University of California Santa Cruz • Office of Technology Transfer

Mutant IDH1 inhibitors useful for treating cancer

07-07-2020 • US-10703746-B2

BOXER, MATTHEW BRIAN • ROHDE, JASON MATTHEW • PRAGANI, RAJAN • LIU, LI • DAVIS, MINDY IRENE EMILY • BRIMACOMBE, KYLE RYAN • SHEN, MIN • SIMEONOV, ANTON • KARAVADHI, SURENDRA • URBAN, DANIEL JASON • JADHAV, AJIT • WANG, XIAODONG • MCIVER, ANDREW LOUIS

University of North Carolina at Chapel Hill • US Department of Health and Human Services

Device and methods of using device for detection of hyperammonemia

14-04-2020 • US-10620187-B2

AYYUB, OMAR BILAL • BEHRENS, ADAM MICHAEL • KOFINAS, PETER • SUMMAR, MARSHALL LYNN • CABRERA-LUQUE, JUAN MANUEL • CUNNINGHAM, GARY • SIMEONOV, ANTON • MARUGAN, JUAN

Childrens National Medical Center Inc • University of Maryland College Park • US Department of Health and Human Services

Device and methods of using device for detection of aminoacidopathies

27-08-2019 • US-10392646-B2

AYYUB, OMAR BILAL • BEHRENS, ADAM MICHAEL • KOFINAS, PETER • SUMMAR, MARSHALL LYNN • CABRERA-LUQUE, JUAN MANUEL • CUNNINGHAM, GARY • SIMEONOV, ANTON • MARUGAN, JUAN

Childrens National Medical Center Inc • University of Maryland College Park • US Department of Health and Human Services

Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

16-07-2019 • US-10351532-B2

MALONEY, DAVID J. • WATERSON, ALEX GREGORY • BANTUKALLU, GANESH RAI • BRIMACOMBE, KYLE RYAN • CHRISTOV, PLAMEN • DANG, CHI V. • DARLEY-USMAR, VICTOR • HU, XIN • JADHAV, AJIT • JANA, SOMNATH • KIM, KWANGHO • KOUZNETSOVA, JENNIFER L. • MOORE, WILLIAM J. • MOTT, BRYAN T. • NECKERS, LEONARD M. • SIMEONOV, ANTON • SULIKOWSKI, GARY ALLEN • URBAN, DANIEL JASON • YANG, SHYH MING

UAB Research Foundation • University of Pennsylvania Penn • Vanderbilt University • US Department of Health and Human Services

Inhibitors of human 12/15-lipoxygenase

14-05-2019 • US-10287279-B2

VAN LEYEN, KLAUS JOACHIN • HOLMAN, THEODORE R. • MALONEY, DAVID J. • JADHAV, AJIT • SIMEONOV, ANTON • RAI, GANESHA

General Hospital Corp • Childrens Hospital Corp • University of California San Diego UCSD • US Department of Health and Human Services

4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

23-04-2019 • US-10266488-B2

MALONEY, DAVID J. • LUCI, DIANE K. • JADHAV, AJIT • HOLMAN, THEODORE • NADLER, JERRY L. • HOLINSTAT, MICHAEL • TAYLOR-FISHWICK, DAVID • SIMEONOV, ANTON • YASGAR, ADAM • MCKENZIE, STEVEN

Thomas Jefferson University • Eastern Virginia Medical School • University of California Santa Cruz • US Department of Health and Human Services • Office of Technology Transfer

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