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Explore MTEC's network of innovators, investors, and research organizations—along with patents and funding opportunities—advancing medical technologies for military and civilian health.

Showing 16 Patents
Inhibitors of the USP1/UAF1 deubiquitinase complex and uses thereof

31-10-2017 • US-9802904-B2

MALONEY, DAVID J. • ROSENTHAL, ANDREW S. • JADHAV, AJIT • DEXHEIMER, THOMAS S. • SIMEONOV, ANTON • ZHUANG, ZHIHAO • LIANG, QIN • LUCI, DIANE K.

University of Delaware • US Department of Health and Human Services

Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

13-02-2024 • US-11897845-B2

MALONEY, DAVID J. • WATERSON, ALEX GREGORY • BANTUKALLU, GANESH RAI • BRIMACOMBE, KYLE RYAN • CHRISTOV, PLAMEN • DANG, CHI V. • DARLEY-USMAR, VICTOR • HU, XIN • JADHAV, AJIT • JANA, SOMNATH • KIM, KWANGHO • KOUZNETSOVA, JENNIFER L. • MOORE, WILLIAM J. • MOTT, BRYAN T. • NECKERS, LEONARD M. • SIMEONOV, ANTON • SULIKOWSKI, GARY ALLEN • URBAN, DANIEL JASON • YANG, SHYH MING

UAB Research Foundation • University of Pennsylvania Penn • Vanderbilt University • US Department of Health and Human Services

Treatment for Wolfram syndrome and other endoplasmic reticulum stress disorders

30-08-2022 • US-11426415-B2

URANO, FUMIHIKO • MAHADEVAN, JANA • CLARK, AMY • JADHAV, AJIT • MALONEY, DAVID • HARVEY, BRANDON • YANG, SHYH-MING • HENDERSON, MARK

Washington University in St Louis WUSTL • US Department of Health and Human Services • Office of Technology Transfer

4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

15-03-2022 • US-11274077-B2

MALONEY, DAVID J. • LUCI, DIANE K. • JADHAV, AJIT • HOLMAN, THEODORE • NADLER, JERRY L. • HOLINSTAT, MICHAEL • TAYLOR-FISHWICK, DAVID • SIMEONOV, ANTON • YASGAR, ADAM • MCKENZIE, STEVEN

United States, Department Of Health • Thomas Jefferson University • Eastern Virginia Medical School • University of California Santa Barbara UCSB • University of California Santa Cruz • US Department of Health and Human Services

Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

15-02-2022 • US-11247971-B2

MALONEY, DAVID J. • WATERSON, ALEX GREGORY • BANTUKALLU, GANESH RAI • BRIMACOMBE, KYLE RYAN • CHRISTOV, PLAMEN • DANG, CHI V. • DARLEY-USMAR, VICTOR • HU, XIN • JADHAV, AJIT • JANA, SOMNATH • KIM, KWANGHO • KOUZNETSOVA, JENNIFER L. • MOORE, WILLIAM J. • MOTT, BRYAN T. • NECKERS, LEONARD M. • SIMEONOV, ANTON • SULIKOWSKI, GARY ALLEN • URBAN, DANIEL JASON • YANG, SHYH MING

UAB Research Foundation • University of Pennsylvania Penn • Vanderbilt University • US Department of Health and Human Services

Pyridazinones and their use in the treatment of cancer

07-09-2021 • US-11110089-B2

ARNÉR, ELIAS SET JENÖ • STAFFORD, WILLIAM CHESTER • COUSSENS, NATHAN PATRICK • LUCI, DIANE KAREN • MALONEY, DAVID JOSEPH • SIMEONOV, ANTON • JADHAV, AJIT • DEXHEIMER, THOMAS S.

Elias Set Jeno Arner • US Department of Health and Human Services

Small molecule BET bromodomain inhibitors and uses thereof

08-06-2021 • US-11028079-B2

STROVEL, JEFFREY WILLIAM • YOSHIOKA, MAKOTO • MALONEY, DAVID J. • YANG, SHYH • JADHAV, AJIT • URBAN, DANIEL JASON

Convergene LLC • ConverGene LLC • US Department of Health and Human Services

Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

30-03-2021 • US-10961200-B2

MALONEY, DAVID J. • WATERSON, ALEX GREGORY • BANTUKALLU, GANESH RAI • BRIMACOMBE, KYLE RYAN • CHRISTOV, PLAMEN • DANG, CHI V. • DARLEY-USMAR, VICTOR • HU, XIN • JADHAV, AJIT • JANA, SOMNATH • KIM, KWANGHO • KOUZNETSOVA, JENNIFER L. • MOORE, WILLIAM J. • MOTT, BRYAN T. • NECKERS, LEONARD M. • SIMEONOV, ANTON • SULIKOWSKI, GARY ALLEN • URBAN, DANIEL JASON • YANG, SHYH MING

UAB Research Foundation • University of Pennsylvania Penn • Vanderbilt University • US Department of Health and Human Services

1 H-pyrazol-1-yl-thiazoles as inhibitors of lactate dehydrogenase and methods of use thereof

23-03-2021 • US-10954228-B2

MALONEY, DAVID J. • WATERSON, ALEX GREGORY • BANTUKALLU, GANESHA RAI • BRIMACOMBE, KYLE RYAN • CHRISTOV, PLAMEN • DANG, CHI V. • DARLEY-USMAR, VICTOR M. • HALL, MATTHEW • HU, XIN • JADHAV, AJIT • JANA, SOMNATH • KIM, KWANGHO • MOORE, WILLIAM J. • MOTT, BRYAN T. • NECKERS, LEONARD M. • SIMEONOV, ANTON • SULIKOWSKI, GARY ALLEN • URBAN, DANIEL JASON • YANG, SHYH MING

UAB Research Foundation • University of Pennsylvania Penn • Vanderbilt University • National Institutes of Health NIH

Thiazole derivatives useful as mutant IDH1 inhibitors for treating cancer

17-11-2020 • US-10836759-B2

BOXER, MATTHEW BRIAN • WANG, XIAODONG • BRIMACOMBE, KYLE RYAN • DAVIS, MINDY IRENE EMILY • FANG, YUHONG • HALL, MATTHEW • JADHAV, AJIT • KARAVADHI, SURENDRA • LIU, LI • MARTINEZ, NATALIA • MCIVER, ANDREW LOUIS • PRAGANI, RAJAN • ROHDE, JASON MATTHEW • SIMEONOV, ANTON • ZHAO, WEI • SHEN, MIN

University of North Carolina at Chapel Hill • US Department of Health and Human Services

4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

25-08-2020 • US-10752581-B2

MALONEY, DAVID J. • LUCI, DIANE K. • JADHAV, AJIT • HOLMAN, THEODORE • NADLER, JERRY L. • HOLINSTAT, MICHAEL • TAYLOR-FISHWICK, DAVID • SIMEONOV, ANTON • YASGAR, ADAM • MCKENZIE, STEVEN

United States, Department Of Health • Thomas Jefferson University • Eastern Virginia Medical School • University of California Santa Barbara UCSB • University of California Santa Cruz • Office of Technology Transfer

Mutant IDH1 inhibitors useful for treating cancer

07-07-2020 • US-10703746-B2

BOXER, MATTHEW BRIAN • ROHDE, JASON MATTHEW • PRAGANI, RAJAN • LIU, LI • DAVIS, MINDY IRENE EMILY • BRIMACOMBE, KYLE RYAN • SHEN, MIN • SIMEONOV, ANTON • KARAVADHI, SURENDRA • URBAN, DANIEL JASON • JADHAV, AJIT • WANG, XIAODONG • MCIVER, ANDREW LOUIS

University of North Carolina at Chapel Hill • US Department of Health and Human Services

Bicyclic BET bromodomain inhibitors and uses thereof

17-12-2019 • US-10508106-B2

STROVEL, JEFFREY WILLIAM • YOSHIOKA, MAKOTO • MALONEY, DAVID J. • YANG, SHYH MING • JADHAV, AJIT • URBAN, DANIEL JASON

ConverGene LLC • US Department of Health and Human Services • Government of the United States of America

Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

16-07-2019 • US-10351532-B2

MALONEY, DAVID J. • WATERSON, ALEX GREGORY • BANTUKALLU, GANESH RAI • BRIMACOMBE, KYLE RYAN • CHRISTOV, PLAMEN • DANG, CHI V. • DARLEY-USMAR, VICTOR • HU, XIN • JADHAV, AJIT • JANA, SOMNATH • KIM, KWANGHO • KOUZNETSOVA, JENNIFER L. • MOORE, WILLIAM J. • MOTT, BRYAN T. • NECKERS, LEONARD M. • SIMEONOV, ANTON • SULIKOWSKI, GARY ALLEN • URBAN, DANIEL JASON • YANG, SHYH MING

UAB Research Foundation • University of Pennsylvania Penn • Vanderbilt University • US Department of Health and Human Services

Inhibitors of human 12/15-lipoxygenase

14-05-2019 • US-10287279-B2

VAN LEYEN, KLAUS JOACHIN • HOLMAN, THEODORE R. • MALONEY, DAVID J. • JADHAV, AJIT • SIMEONOV, ANTON • RAI, GANESHA

General Hospital Corp • Childrens Hospital Corp • University of California San Diego UCSD • US Department of Health and Human Services

4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

23-04-2019 • US-10266488-B2

MALONEY, DAVID J. • LUCI, DIANE K. • JADHAV, AJIT • HOLMAN, THEODORE • NADLER, JERRY L. • HOLINSTAT, MICHAEL • TAYLOR-FISHWICK, DAVID • SIMEONOV, ANTON • YASGAR, ADAM • MCKENZIE, STEVEN

Thomas Jefferson University • Eastern Virginia Medical School • University of California Santa Cruz • US Department of Health and Human Services • Office of Technology Transfer

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