Gladstone Institutes
Gladstone Institutes is an independent biomedical research organization dedicated to tackling the biggest challenges in human health. By disrupting traditional scientific methods, Gladstone aims to make groundbreaking discoveries that can transform lives. The organization is renowned for its innovative approaches in research, focusing on conditions with significant medical, economic, and social impacts. Founded in 1979 from a donation by J. David Gladstone, the institute has expanded its research areas to include cardiovascular, neurological, and viral diseases, as well as data science and biotechnology.
Gladstone Institutes
1650 Owens Street, San Francisco, CA 94158
Patents
Compositions and methods for reactivating latent immunodeficiency virus
2023-11-07 • US-11807852-B2
View DetailsS-enantiomers of beta-hydroxybutyrate and butanediol and methods for using same
2023-10-03 • US-11773051-B2
View DetailsIn vitro methods of differentiating stem cells into neurons and neurons generated using the same
2023-07-18 • US-11702630-B2
View DetailsMedium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same
2023-03-21 • US-11608308-B2
View DetailsCompositions and methods for reactivating latent immunodeficiency virus using a GSK-3 inhibitor
2023-02-28 • US-11590110-B2
View DetailsMethods and compositions for generating a deletion library and for identifying a defective interfering particle (DIP)
2023-02-21 • US-11584931-B2
View DetailsCompositions and methods for in vitro assays of fibrin activity
2023-02-07 • US-11573222-B2
View DetailsModified non-natural NKG2D ligands that selectively deliver attached heterologous molecules to non-natural NKG2D receptors on car-cells
2022-09-13 • US-11440948-B2
View DetailsMethods and compositions for treating obesity and/or diabetes and for identifying candidate treatment agents
2022-07-05 • US-11376242-B2
View DetailsMethods of treating disease by metabolic control of T-cell differentiation
2022-02-08 • US-11241455-B2
View DetailsCompositions and methods for reactivating latent immunodeficiency virus
2021-08-24 • US-11098309-B2
View DetailsMedium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same
2021-01-12 • US-10889538-B2
View DetailsWhat We Do
Focuses on congenital heart disease, heart failure, genetic diseases, and regenerative medicine.
Specializes in artificial intelligence, computational biology, CRISPR genome editing, genetic diseases, proteomics, and synthetic biology.
Researches cancer, autoimmune diseases, infectious diseases, and primary immunodeficiencies.
Studies Alzheimer's disease, other dementias, ALS, autism, epilepsy, Huntington’s disease, long COVID, multiple sclerosis, Parkinson’s disease, rare brain diseases, spinal cord injury, and traumatic brain injury.
Focuses on HIV/AIDS, antimicrobial-resistant infections, COVID-19 and long COVID, women’s health, influenza, microbiome and gut health, phage therapy, respiratory viruses, hepatitis C, vaccine development, Zika, and malaria.
Provides services for assay development and drug discovery.
Application Area
Infectious Diseases
Biologics
Diagnostics
Services
Funded Projects
Reduction of HIV Prevalence and Incidence Using TIPs: Single-administration, Escape-Resistant Antivirals for Resource-limited Settings
TIPs reduce HIV by 100-fold in mice, show broad efficacy and safety, and resist mutation.
News & Updates
Recognizes individuals whose research has advanced cellular reprogramming technology for regenerative medicine.
Gladstone researcher receives prize to study blood-brain barrier dysfunction and its impact on neurological disease.
Discusses the impact of NIH funding cuts on scientific discovery and public health.
The three awardees of the Outstanding Mentoring Award share their insights on the transformative power of mentorship in shaping the next generation of scientists.
The impactful summer internship program, created at Gladstone Institutes, immerses select undergraduates in cutting-edge science.
In early 2024, Deanna Necula co-chaired a prestigious Gordon Research Seminar in Ventura, California.