Member

HDT Bio


HDT Bio is a clinical-stage biopharmaceutical company based in Seattle, developing novel technologies and products designed to harness and enhance the immune system for the treatment and prevention of cancer and infectious diseases. HDT Bio utilizes advanced immunotherapeutic platforms, including a proprietary nanoparticle delivery system, to provide safe, potent, and durable solutions that enable rapid clinical translation and personalized cancer therapies. The company's multidisciplinary team and international partnerships facilitate robust clinical development, innovative product design, and global distribution with the goal of improving patient outcomes worldwide.

Industries

Biotechnology

Nr. of Employees

small (1-50)

HDT Bio

1150 Eastlake Ave E, Suite 200A, Seattle, WA 98109

HDT Bio is currently seeking investment

HDT Bio is seeking a seed investment in the range of 5m-20m

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Patents

Detection of desmoglein-2 in cancers of epithelial origin

2026-06-30 • US-12669505-B2

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Cancer therapy compositions and uses thereof

2025-12-02 • US-12485163-B2

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Compositions and methods for delivery of RNA

2025-10-07 • US-12433957-B2

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RNA vaccines against infectious diseases

2025-07-08 • US-12350329-B2

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SARS-CoV-2 RNA vaccine compositions and methods of use

2025-03-25 • US-12257299-B2

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Dried nanoparticle compositions

2025-02-25 • US-12233160-B2

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Products

Vaccine candidate targeting breast cancer using immunotherapeutic platform.

Immunotherapy vaccine candidate for glioblastoma based on targeted antigens.

Vaccine targeting prostate cancer antigens to elicit an immune response.

Immunotherapy platform-based candidate for prevention and treatment of pancreatic cancer.

RNA-based vaccine targeting SARS-CoV-2, demonstrating favorable safety and immunogenicity in clinical use.

Self-amplifying RNA, nanoparticle-delivered vaccine in clinical development for CCHF virus.

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Expertise Areas

  • Immuno-oncology
  • RNA and DNA-based vaccine development
  • Nanoparticle drug delivery
  • Infectious disease vaccine research
  • Show More (4)

Key Technologies

  • Self-amplifying replicon RNA
  • Nanoparticle-based delivery systems
  • Viral vector genome engineering
  • TLR3 and RIG-I pathway activation
  • Show More (2)

Key People

Co-Founder & CEO

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Chief Development Officer

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SVP, Strategic Operations

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SVP, Research Operations

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Director, Funding Management

Director, Formulations

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News & Updates

Study in preclinical models showing efficacy of a self-amplifying RNA vaccine against enterovirus D68.

Durability of protective immunity induced by a replicon RNA vaccine demonstrated in animal models.

Milestone announced in efforts to advance brain cancer immunotherapy research.

Initiation of a clinical program using immunotherapy for brain cancer at McGill University.

Awarded for development and advancement of a CCHF vaccine candidate from lab to clinical stage.


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