EuMentis Therapeutics


EuMentis Therapeutics is a clinical stage biopharmaceutical company dedicated to developing novel therapies for serious neuropsychiatric conditions. The company integrates clinically validated science with cutting-edge technology to create effective treatments for conditions like Tourette syndrome and autism spectrum disorder, focusing on restoring balance in neurotransmitter systems.

Eumentis Therapeutics

EuMentis Therapeutics


What We Do

EM-221

A novel PDE10A inhibitor designed to reduce dopamine signaling in patients with Tourette syndrome, aiming to alleviate motor and vocal tics without the side effects associated with current FDA-approved medications.

EM-113

A noncompetitive, low-trapping glutamate antagonist aimed at treating autism spectrum disorder by restoring glutamate equilibrium without causing serious side effects.

NMDA Antagonist for Traumatic Brain Injury

A treatment under development to address the excess glutamate released after traumatic brain injury, which can lead to further neuronal damage.


Psychological and Cognitive Health and Performance

Regenerative Medicine

Digital Health Technologies


Key People

Mark A. Tepper, PhD

President & CEO

Randall Marshall, MD

Chief Medical Officer

Joanne Emmett

Head of Clinical Operations

Xiaoming Zhang, PhD

Head of CMC

Dylan Wenke

VP of Finance and Operations


News & Updates

Randall Marshall, MD, will present at the Tourette Association of America’s TIC-CON24 Research Symposium in Dallas, Texas.

Randall Marshall, MD, will present a keynote address at the Autism Parenting Summit held virtually.

EuMentis Therapeutics Inc. received a $3 million award from the United States Department of Defense to advance its novel NMDA receptor antagonist for traumatic brain injury.