Astrocyte Pharmaceuticals Inc.


Astrocyte Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company dedicated to developing innovative neuroprotection therapies for traumatic brain injuries (TBI), concussions, stroke, and neurodegenerative disorders. The company focuses on harnessing the potential of astrocytes, the brain's natural caretaker cells, to treat brain injuries and diseases. Their flagship program, AST-004, aims to significantly reduce early brain damage and is advancing to Phase 2 clinical trials.

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Astrocyte Pharmaceuticals Inc.

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What We Do

Astrocyte Pharmaceuticals develops therapies for traumatic brain injuries, concussions, stroke, and neurodegenerative disorders by leveraging the potential of astrocytes.

AST-004 is a novel small molecule candidate in clinical trials for treating acute ischemic stroke, TBI, concussion, and neurodegenerative diseases. It has shown promise in reducing brain lesion growth and damage.



Key People

Co-Founder and Chief Executive Officer

Co-Founder and Advisor

Vice-President of Research

Chief Medical Advisor

Vice-President of Clinical Development Operations


Funded Projects

Astrocyte Announces Initiation of First-In-Human Phase 1 Study of the Promising Stroke and Traumatic Brain Injury Therapeutic, AST-004

Astrocyte Pharmaceuticals has begun a Phase 1 trial for AST-004, a potential treatment for stroke, TBI, and neurodegenerative diseases. The study, funded partly by MTEC and the U.S. Army, will assess safety in 52 healthy participants. If successful, it will progress to Phase 2 trials.


News & Updates

Astrocyte Pharmaceuticals was named 'Innovator of the Month' by Senator Chris Murphy for their work in advancing cerebroprotective therapies.

Astrocyte Pharmaceuticals received FDA clearance for its Investigational New Drug Application for AST-004, paving the way for Phase 2 trials.

The Alzheimer’s Drug Discovery Foundation joined Astrocyte Pharmaceuticals’ $6M+ pre-Series B financing round to expand the development of AST-004.

Theodore Liston, Ph.D., Vice President of Research at Astrocyte, received the 2022 Innovation and Progress Award from the journal Stroke for his work on AST-004.