ZabBio Inc.


ZabBio develops monoclonal antibody-based therapeutics targeting infectious diseases and reproductive health, with an emphasis on scalable, low-cost production for large markets. The company is developing a human contraceptive antibody formulated as a vaginal film (ZB-06); a Phase 1 clinical trial was completed in 2022 and a dose-finding Phase 2a was planned for 2024. The ZB-06 program is a collaborative, grant-funded project involving academic and industry partners.

Industries

health-care
manufacturing
medical
pharmaceutical

Nr. of Employees

small (1-50)


Products

ZB-06 (human contraceptive antibody)

A human monoclonal antibody formulated as a vaginal film intended for on-demand female contraception. The antibody agglutinates sperm and traps sperm in cervical mucus to prevent ascent and fertilization.

Expertise Areas

  • Monoclonal antibody development
  • Contraceptive product development
  • Reproductive health therapeutics
  • Early-phase clinical trials
  • Show More (3)

Key Technologies

  • Monoclonal antibody therapeutics
  • Vaginal film drug delivery
  • Antibody-mediated agglutination mechanisms
  • Clinical trial operations (Phase 1/2a)
  • Show More (1)

News & Updates

Press release announcing IND opening for the contraceptive antibody program.

News item linking to external coverage about antibody development for acute flaccid myelitis.

Phase 1 clinical trial of the contraceptive antibody formulated as a vaginal film was completed in 2022 at the Jones Institute for Reproductive Medicine (EVMS).

ZB-06 program is funded by an NICHD Contraceptive Research Center grant (2P50HD096957-02) and conducted in collaboration with academic and industry partners.


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