Wistar Institute
The Wistar Institute is a global leader in biomedical research, focusing on cancer, immunology, infectious diseases, and vaccine development. It aims to solve challenging health problems through innovative research, collaboration, and education, translating discoveries into therapies and vaccines to improve human health.
Industries
Nr. of Employees
large (251-1000)
Wistar Institute
Patents
Adenoviral vectors encoding hepatitis b viral antigens fused to herpes virus glycoprotein d and methods of using the same
US-12290561-B2
View Details
Adenoviral vectors encoding hepatitis b viral antigens fused to herpes virus glycoprotein d and methods of using the same
US-12290561-B2
View DetailsProducts
Nucleic-acid vaccine candidates (research-stage)
Research-stage DNA-based vaccine constructs developed and evaluated in preclinical models, with at least one candidate advanced to Phase I clinical testing.
Monoclonal antibody constructs (research-stage)
Engineered monoclonal antibody constructs developed for antiviral and immuno-oncology applications using DNA-encoded and recombinant approaches.
NextSeq 2000
High-throughput next-generation sequencing system supporting various genomic applications including gene expression analysis, RNA-seq, and targeted sequencing.
Molecular Stratification Assay for Glioblastoma using Isoform-Level Gene Signatures
A diagnostic system using transcript/isoform-based gene expression profiling via RT-qPCR on 121 distinct transcripts to stratify GBM patients and predict prognosis.
nCounter Analysis System
Multiplexed digital quantification platform for nucleic acids without requiring sample amplification.
QX200 Droplet Digital PCR System
Digital PCR system that enables absolute quantification of targets by partitioning a qPCR reaction into millions of picoliter-sized droplets.
Nucleic-acid vaccine candidates (research-stage)
Research-stage DNA-based vaccine constructs developed and evaluated in preclinical models, with at least one candidate advanced to Phase I clinical testing.
Monoclonal antibody constructs (research-stage)
Engineered monoclonal antibody constructs developed for antiviral and immuno-oncology applications using DNA-encoded and recombinant approaches.
NextSeq 2000
High-throughput next-generation sequencing system supporting various genomic applications including gene expression analysis, RNA-seq, and targeted sequencing.
Molecular Stratification Assay for Glioblastoma using Isoform-Level Gene Signatures
A diagnostic system using transcript/isoform-based gene expression profiling via RT-qPCR on 121 distinct transcripts to stratify GBM patients and predict prognosis.
nCounter Analysis System
Multiplexed digital quantification platform for nucleic acids without requiring sample amplification.
QX200 Droplet Digital PCR System
Digital PCR system that enables absolute quantification of targets by partitioning a qPCR reaction into millions of picoliter-sized droplets.
Services
Sequencing and genomics workflows for research projects, with data generation and support for downstream analysis.
Multiparameter flow cytometry and cell sorting services including experimental setup and data analysis support.
Microscopy instrumentation and image analysis support for cellular and tissue imaging experiments.
Mass-spectrometry-based proteome and metabolome profiling, sample processing and data analysis.
High-throughput screening and recombinant protein expression to support target discovery and assay development.
Tissue processing, embedding, sectioning and staining to support histological analysis.
Sequencing and genomics workflows for research projects, with data generation and support for downstream analysis.
Multiparameter flow cytometry and cell sorting services including experimental setup and data analysis support.
Microscopy instrumentation and image analysis support for cellular and tissue imaging experiments.
Mass-spectrometry-based proteome and metabolome profiling, sample processing and data analysis.
High-throughput screening and recombinant protein expression to support target discovery and assay development.
Tissue processing, embedding, sectioning and staining to support histological analysis.
Expertise Areas
- Vaccine development
- Immunotherapy and immuno-oncology
- Cancer basic and translational research
- HIV cure and viral diseases research
Key Technologies
- Nucleic-acid (DNA) vaccine platforms
- Synthetic nucleic-acid technology
- Monoclonal antibody engineering
- Next-generation sequencing (NGS)
News & Updates
The Wistar Institute commemorated the milestone expansion and opening of its HIV Cure and Viral Diseases Center.
Dr. Jesper Pallesen uses cryo-electron microscopy to view protein structures at the atomic level.
Dr. Ian Tietjen, education director, discusses his return to Africa and global health initiatives.
Announcement of Joshua Friedman joining the Wistar Board of Trustees.
Research by Wistar scientists on viral immune evasion mechanisms.
First independent biomedical research institute in the U.S.
Founded in 1892, Wistar was the first independent biomedical research institute in the United States.
The Wistar Institute commemorated the milestone expansion and opening of its HIV Cure and Viral Diseases Center.
Dr. Jesper Pallesen uses cryo-electron microscopy to view protein structures at the atomic level.
Dr. Ian Tietjen, education director, discusses his return to Africa and global health initiatives.
Announcement of Joshua Friedman joining the Wistar Board of Trustees.
Research by Wistar scientists on viral immune evasion mechanisms.
First independent biomedical research institute in the U.S.
Founded in 1892, Wistar was the first independent biomedical research institute in the United States.