The David J. Gladstone Institutes
Gladstone Institutes is an independent biomedical research organization dedicated to tackling the biggest challenges in human health. By disrupting traditional scientific methods, Gladstone aims to make groundbreaking discoveries that can transform lives. The organization is renowned for its innovative approaches in research, focusing on conditions with significant medical, economic, and social impacts. Founded in 1979 from a donation by J. David Gladstone, the institute has expanded its research areas to include cardiovascular, neurological, and viral diseases, as well as data science and biotechnology.
Industries
Nr. of Employees
large (251-1000)
The David J. Gladstone Institutes
1650 Owens Street, San Francisco, CA 94158
Patents
Products
Cardiovascular Disease Institute
Focuses on research related to heart diseases.
Data Science and Biotechnology Institute
Concentrates on integrating data science and biotechnology for biomedical research.
Genomic Immunology Institute
Dedicated to studying the genomic aspects of the immune system.
Neurological Disease Institute
Targets research on diseases affecting the brain and nervous system.
Virology Institute
Specializes in research on viruses and viral diseases.
Assay Development and Drug Discovery Core
Provides services for developing assays and discovering drugs.
Cardiovascular Disease Institute
Focuses on research related to heart diseases.
Data Science and Biotechnology Institute
Concentrates on integrating data science and biotechnology for biomedical research.
Genomic Immunology Institute
Dedicated to studying the genomic aspects of the immune system.
Neurological Disease Institute
Targets research on diseases affecting the brain and nervous system.
Virology Institute
Specializes in research on viruses and viral diseases.
Assay Development and Drug Discovery Core
Provides services for developing assays and discovering drugs.
Services
Instrument access, experimental design and panel setup support, antibody titration guidance, hands-on operation and software training, multi-parameter data acquisition, and downstream analysis assistance.
Sequencing and single-cell assay services, low-input and strand-specific library-preparation support, consultation on reagent and automation platforms, and integration with computational pipelines.
Protein identification, quantification, and method development using mass spectrometry instrumentation and proteomics workflows.
Collaborative projects to design, validate, and screen biological assays and to support progression of targets through early translational research stages.
Custom computational pipelines, data-management services, machine-learning approaches, and multi-omics integration for analysis and interpretation of complex biological datasets.
Tissue processing, sectioning, staining, and light-microscopy imaging to support experiments requiring image-based analysis.
Instrument access, experimental design and panel setup support, antibody titration guidance, hands-on operation and software training, multi-parameter data acquisition, and downstream analysis assistance.
Sequencing and single-cell assay services, low-input and strand-specific library-preparation support, consultation on reagent and automation platforms, and integration with computational pipelines.
Protein identification, quantification, and method development using mass spectrometry instrumentation and proteomics workflows.
Collaborative projects to design, validate, and screen biological assays and to support progression of targets through early translational research stages.
Custom computational pipelines, data-management services, machine-learning approaches, and multi-omics integration for analysis and interpretation of complex biological datasets.
Tissue processing, sectioning, staining, and light-microscopy imaging to support experiments requiring image-based analysis.
Expertise Areas
- Single-cell genomics and immune-repertoire analysis
- High-throughput sequencing assay development
- High-parameter cytometry and immunophenotyping
- Computational biology and machine-learning for multi-omics
Key Technologies
- Single-cell RNA sequencing and single-cell multi-omics
- scATAC-seq and single-cell data integration
- V(D)J immune-repertoire sequencing
- Next-generation sequencing and low-input library chemistries
News & Updates
Celebrate the work of 14 interns from Gladstone's PUMAS program, which provides lab experience to underrepresented community college students.
An event bringing together top researchers to discuss advancements in Alzheimer's research.
A session by Robert Mahley on how to give effective scientific presentations.
A seminar on titrating antibodies and dealing with data considerations in flow cytometry.
A seminar on analyzing flow cytometry data, including plots, gates, and statistics.
A neuroscience seminar by Li Gan on neuroimmune interactions in neurodegeneration.
Celebrate the work of 14 interns from Gladstone's PUMAS program, which provides lab experience to underrepresented community college students.
An event bringing together top researchers to discuss advancements in Alzheimer's research.
A session by Robert Mahley on how to give effective scientific presentations.
A seminar on titrating antibodies and dealing with data considerations in flow cytometry.
A seminar on analyzing flow cytometry data, including plots, gates, and statistics.
A neuroscience seminar by Li Gan on neuroimmune interactions in neurodegeneration.