VPCIR Biosciences


VPCIR Biosciences is a spin-out from Aarhus University, Denmark, with 20 years of development in technology capable of detecting living pathogens in saliva. The company is focused on developing faster, cheaper, and non-invasive diagnostic tests, starting with tuberculosis and expanding to other infectious diseases, using innovative lateral flow tests and proprietary technology.

Industries

biotechnology
health-care
health-diagnostics
medical
medical-device

Nr. of Employees

small (1-50)

VPCIR Biosciences

Bloustrødvej 24, DK-2970 Hørsholm, Denmark


Products

Saliva-based lateral flow tuberculosis test (planned availability 2025)

A point-of-care lateral flow test designed to detect active tuberculosis from saliva using enzyme-activity based sensing, intended to be non-invasive and low-cost for field use.

Rolling circle amplification activity kit (research/assay kit)

A laboratory kit/workflow demonstrating RCA-based detection of topoisomerase and other enzyme activities in biological samples for research and assay development.

DNA sensor platform for viral integrase and retrovirus detection

A DNA sensor approach that translates integrase-mediated integration events into RCA templates for highly sensitive detection and discrimination of retroviruses.


Services

Protocol development and on-site execution of field trials comparing enzyme-activity diagnostics to reference molecular tests and monitoring treatment response.

Design and optimization of enzyme-activity based assays with pump-free microfluidic extraction and visual/colorimetric outputs for point-of-care use.

Support for developing QMS and processes aligned with ISO 13485 and IVDR requirements to prepare diagnostics for CE marking and market entry.

Expertise Areas

  • Enzyme-activity based diagnostics
  • Point-of-care lateral flow diagnostics
  • Saliva-based infectious disease testing
  • Rolling circle amplification assay development
  • Show More (6)

Key Technologies

  • Rolling circle amplification (RCA)
  • Lateral flow assays
  • Droplet microfluidics
  • Molecular beacons (fluorometric probes)
  • Show More (6)

News & Updates

A study conducted from February to September 2023 to evaluate the REEAD technology for TB diagnosis in Oman.

Introduction of a saliva-based malaria diagnostic method using droplet microfluidics and DNA sensors.

A novel assay using droplet microfluidics to detect malaria parasite enzyme activity in blood samples.

A new DNA sensor system employing rolling circle amplification for sensitive and specific detection of retroviruses like HIV.

A novel molecular assay for malaria detection in saliva, utilizing enzyme activity and colorimetric detection.

A sensitive assay based on topoisomerase IA activity for detecting tuberculosis bacteria in small biological samples.

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