C4Diagnostics
C4Diagnostics is a French-based biotech company founded in 2017, specializing in the development of in vitro diagnostic (IVD) tests for human infectious diseases. The company aims to provide rapid, reliable, and highly sensitive diagnostic solutions to improve patient care and combat antimicrobial resistance. It leverages proprietary click-chemistry technology and RT-LAMP technology in its portfolio of diagnostic tests, which include solutions for infectious diseases such as Legionnaires’ Disease, urinary tract infections, antimicrobial susceptibility testing, and COVID-19. C4Diagnostics is ISO 13485 certified and actively collaborates with research and industrial partners to innovate in the field of infectious disease diagnostics.
Industries
Nr. of Employees
small (1-50)
C4Diagnostics
Marseille, Provence-Alpes-Cote d'Azur, France, Europe
Products
Phenotypic click-chemistry microbial labeling and enrichment platform
A platform that uses metabolizable synthetic sugars and click-chemistry to label live culturable microorganisms for detection, fluorescent/enzymatic tagging or magnetic-bead enrichment prior to downstream analysis.
Saliva-based RT-LAMP molecular SARS-CoV-2 test (CE marked)
RT-LAMP molecular assay optimized for saliva with internal control and two gene targets, intended for professional laboratory use with a reported time-to-result up to 30 minutes.
Rapid lateral flow assay for Legionella pneumophila detection with electronic reader
A lateral flow assay workflow for qualitative detection of Legionella pneumophila across all serogroups from respiratory samples, designed to be read with a compact device that interfaces with LIMS; reported time-to-result ~48 hours in clinical workflow context.
Rapid urinary tract infection diagnostic based on microcolony detection
A microcolony-based UTI diagnostic workflow that detects and counts microcolonies with the aim of providing same-day results and compatibility with mass-spectrometry identification methods; manual protocol reported at ~8 hours and an automated protocol targeted at ≤6 hours.
Environmental sampling kits (air, surface, wastewater) with validated RT-PCR assays
Off-the-shelf sampling kits for wastewater, air and surface collection, paired with validated high-performance RT-PCR assays and protocols for environmental surveillance and outbreak prevention.
Phenotypic click-chemistry microbial labeling and enrichment platform
A platform that uses metabolizable synthetic sugars and click-chemistry to label live culturable microorganisms for detection, fluorescent/enzymatic tagging or magnetic-bead enrichment prior to downstream analysis.
Saliva-based RT-LAMP molecular SARS-CoV-2 test (CE marked)
RT-LAMP molecular assay optimized for saliva with internal control and two gene targets, intended for professional laboratory use with a reported time-to-result up to 30 minutes.
Rapid lateral flow assay for Legionella pneumophila detection with electronic reader
A lateral flow assay workflow for qualitative detection of Legionella pneumophila across all serogroups from respiratory samples, designed to be read with a compact device that interfaces with LIMS; reported time-to-result ~48 hours in clinical workflow context.
Rapid urinary tract infection diagnostic based on microcolony detection
A microcolony-based UTI diagnostic workflow that detects and counts microcolonies with the aim of providing same-day results and compatibility with mass-spectrometry identification methods; manual protocol reported at ~8 hours and an automated protocol targeted at ≤6 hours.
Environmental sampling kits (air, surface, wastewater) with validated RT-PCR assays
Off-the-shelf sampling kits for wastewater, air and surface collection, paired with validated high-performance RT-PCR assays and protocols for environmental surveillance and outbreak prevention.
Services
Environmental monitoring and laboratory analysis services
End-to-end environmental testing including sample logistics, wastewater/air/surface sampling, high-performance RT-PCR analysis and monitoring campaign reporting for institutions and healthcare facilities.
High-throughput in-house environmental testing unit (batch processing)
Laboratory unit for processing large batches of environmental samples for surveillance programs, wastewater testing strategies and case-study deployments.
Training for sampling and laboratory procedures
Training programs covering environmental sampling (wastewater, air, surfaces) and pre-analytical/analytical laboratory workflows to support implementation of monitoring campaigns.
Assay validation and clinical/field study support
Design and execution support for clinical validation studies and field deployments (including clinical trials for human diagnostics and applied environmental case studies).
Environmental monitoring and laboratory analysis services
End-to-end environmental testing including sample logistics, wastewater/air/surface sampling, high-performance RT-PCR analysis and monitoring campaign reporting for institutions and healthcare facilities.
High-throughput in-house environmental testing unit (batch processing)
Laboratory unit for processing large batches of environmental samples for surveillance programs, wastewater testing strategies and case-study deployments.
Training for sampling and laboratory procedures
Training programs covering environmental sampling (wastewater, air, surfaces) and pre-analytical/analytical laboratory workflows to support implementation of monitoring campaigns.
Assay validation and clinical/field study support
Design and execution support for clinical validation studies and field deployments (including clinical trials for human diagnostics and applied environmental case studies).
Expertise Areas
- Phenotypic assay development for infectious agents
- Antimicrobial susceptibility testing (rapid phenotypic AST)
- In vitro diagnostic (IVD) test development and industrialization
- Environmental microbiology testing and surveillance (wastewater, air, surfaces)
Key Technologies
- Click-chemistry-based metabolic labeling
- Copper-free click chemistry with magnetic bead separation
- Reverse transcription loop-mediated isothermal amplification (RT-LAMP)
- Real-time RT-PCR for environmental surveillance