Topokine Therapeutics
Topokine Therapeutics is a clinical-stage biotechnology company developing topical prescription medications for non-invasive contouring of the face and body. Their lead program, XAF5 Gel, is in Phase 2 clinical development for reducing excess submental fat and other indications. The company also has a pipeline including XAF5 Ointment for eye bags and TAT4, a topical filler therapy.
Industries
Nr. of Employees
small (1-50)
Topokine Therapeutics
Boston, Massachusetts, United States, North America
Patents
Methods and compositions for topical delivery of prostaglandins to subcutaneous fat
US-10869874-B2
View DetailsCompositions and methods for topical delivery of prostaglandins to subcutaneous fat
US-10556012-B2
View Details
Methods and compositions for topical delivery of prostaglandins to subcutaneous fat
US-10869874-B2
View DetailsCompositions and methods for topical delivery of prostaglandins to subcutaneous fat
US-10556012-B2
View DetailsProducts
Topical adipomodulatory gel (Phase 2 clinical development)
Topical gel formulation intended to reduce localized submental adipose tissue; advanced to Phase 2 clinical evaluation for local adipose reduction indications.
Topical ointment for periorbital fat (pipeline)
Topical ointment formulation developed to treat periorbital fat protrusion (steatoblepharon, commonly described as 'eye bags').
Topical tissue-volumizing therapy (pipeline)
Topical agent intended to increase local tissue volume as a non‑invasive alternative to injectable fillers.
Topical adipomodulatory gel (Phase 2 clinical development)
Topical gel formulation intended to reduce localized submental adipose tissue; advanced to Phase 2 clinical evaluation for local adipose reduction indications.
Topical ointment for periorbital fat (pipeline)
Topical ointment formulation developed to treat periorbital fat protrusion (steatoblepharon, commonly described as 'eye bags').
Topical tissue-volumizing therapy (pipeline)
Topical agent intended to increase local tissue volume as a non‑invasive alternative to injectable fillers.
Expertise Areas
- Clinical trial management for topical therapeutics
- Topical formulation and localized drug delivery
- Aesthetic and dermatologic therapeutic development
- Manufacturing technologies for topical pharmaceutical products
Key Technologies
- Topical drug delivery
- Adipomodulatory active agents
- Topical volumizing (filler) therapies
- Formulation of gels and ointments