Thioredoxin Systems


Thioredoxin Systems AB is a Swedish biomedical company dedicated to developing innovative antibiotics to combat antimicrobial resistance. Their flagship product, EbsArgent™, is a novel antibacterial treatment targeting resistant bacterial infections, especially urinary tract infections caused by multidrug-resistant bacteria. The company is committed to advancing medical solutions that address the global health threat of antibiotic resistance, leveraging groundbreaking redox biology research and a strong scientific legacy.

Industries

biotechnology
life-science
medical

Nr. of Employees

small (1-50)

Thioredoxin Systems

Nanna Svartz väg 2, 171 65 Solna, Sweden


Patents

Antibiotic compositions

US-11801262-B2

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Composition comprising selenazol or thiazalone derivatives and silver and method of treatment therewith

US-11013730-B1

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Antibiotic compositions

US-10653717-B2

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Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith

US-10058542-B1

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Products

Combination antibiotic of a selenium-containing small molecule and silver ions for complicated urinary tract infections

A combination therapeutic composed of a small-molecule selenium compound together with low levels of silver ions, developed to irreversibly inhibit bacterial thioredoxin reductase and produce synergistic bactericidal activity against multidrug-resistant pathogens and biofilms; intended for treatment of complicated urinary tract infections.

Expertise Areas

  • Antibiotic drug discovery
  • Redox biology and thioredoxin system research
  • Preclinical in vivo infection models
  • Microbiology and antimicrobial susceptibility testing
  • Show More (4)

Key Technologies

  • Small-molecule antimicrobial agents (selenium-containing compounds)
  • Silver ion-based antimicrobial agents
  • Targeting bacterial thioredoxin reductase
  • Combination therapy formulation
  • Show More (4)

News & Updates

Thioredoxin Systems AB announced the close of a SEK 25 million Series A financing round to support the development of EbsArgent™, a first-in-class antibiotic for urinary tract infections caused by antibiotic-resistant bacteria. The funding will support preclinical studies and Phase I clinical trials.

Thioredoxin Systems AB became a full member of BEAM Alliance, a community of European companies developing innovative products to tackle antimicrobial resistance.

The fundamental aspects of EbsArgent's antimicrobial technology have been awarded a granted patent by the European Patent Office.

The company welcomed Carlos Ratia Loncán as Laboratory Manager, a clinical microbiologist with a PhD from the University of Barcelona.


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