The Jackson Laboratory
The Jackson Laboratory is dedicated to discovering precise genomic solutions for disease, aiming to improve human health through cutting-edge research, education, and innovative biomedical solutions. They focus on genetics, genomics, stem cell science, AI-enabled data science, and predictive biology to accelerate the discovery of life-changing therapies. The organization also conducts space-related research, including studies on genetically engineered mice in microgravity environments, and offers extensive services in mouse models, genomics, and biomedical research. They are also involved in coronavirus research, including developing mouse models for COVID-19, studying long COVID, and understanding the genetic and biological mechanisms underlying coronavirus infection and pathology. Additionally, JAX emphasizes the importance of mouse models in biomedical research, exploring their role in understanding human diseases, and developing new therapies. They are committed to responsible animal research, innovation in digital home cage monitoring, and providing resources and expertise to the scientific community.
Industries
Nr. of Employees
Very Large (1000+)
Products
Curated mouse strain collection
A searchable catalogue of genetically defined mouse strains available for order to support basic and translational research.
Biological materials repository (cells and tissues)
Supply of research-grade biological materials including iPS cells, PDX tumors, mouse tissues, embryos, sperm, and embryonic stem cells.
Clinical genomics knowledge resources
Curated clinical knowledgebase and laboratory outputs to support genomic variant interpretation and clinical decision-making.
Digital home-cage monitoring platform
A continuous in-cage video monitoring and analytics platform providing high-resolution video capture, AI-based behavior classification, individual tracking in socially housed groups, validated digital measures, study workflow tools, and data export capabilities.
Curated coronavirus mouse-model dataset
Downloadable dataset aggregating strains, alleles, genes and publications curated for coronavirus research with ortholog mappings and linked literature.
Pandemic biorepository sample collection
A collection of biological specimens curated during the COVID-19 pandemic for research on pathogen biology, long-term outcomes and therapeutic evaluation.
Curated mouse strain collection
A searchable catalogue of genetically defined mouse strains available for order to support basic and translational research.
Biological materials repository (cells and tissues)
Supply of research-grade biological materials including iPS cells, PDX tumors, mouse tissues, embryos, sperm, and embryonic stem cells.
Clinical genomics knowledge resources
Curated clinical knowledgebase and laboratory outputs to support genomic variant interpretation and clinical decision-making.
Digital home-cage monitoring platform
A continuous in-cage video monitoring and analytics platform providing high-resolution video capture, AI-based behavior classification, individual tracking in socially housed groups, validated digital measures, study workflow tools, and data export capabilities.
Curated coronavirus mouse-model dataset
Downloadable dataset aggregating strains, alleles, genes and publications curated for coronavirus research with ortholog mappings and linked literature.
Pandemic biorepository sample collection
A collection of biological specimens curated during the COVID-19 pandemic for research on pathogen biology, long-term outcomes and therapeutic evaluation.
Services
End-to-end preclinical study support across therapeutic areas using validated animal models and standardized workflows.
Design and production of custom genetically modified models and humanized constructs to meet specific experimental requirements.
Breeding, cryopreservation, cryorecovery, IVF expansion, and genome scanning to maintain and expand research colonies.
Provision and shipment of research-grade biological materials including iPS cells, PDX tumors, tissues, embryos, and stem cells.
Genomic testing, interpretation, and a curated clinical knowledgebase to support precision diagnostics and therapeutic decision-making.
Training programs and short courses teaching coding, biostatistics, data visualization, and computational techniques applied to biomedical problems.
End-to-end preclinical study support across therapeutic areas using validated animal models and standardized workflows.
Design and production of custom genetically modified models and humanized constructs to meet specific experimental requirements.
Breeding, cryopreservation, cryorecovery, IVF expansion, and genome scanning to maintain and expand research colonies.
Provision and shipment of research-grade biological materials including iPS cells, PDX tumors, tissues, embryos, and stem cells.
Genomic testing, interpretation, and a curated clinical knowledgebase to support precision diagnostics and therapeutic decision-making.
Training programs and short courses teaching coding, biostatistics, data visualization, and computational techniques applied to biomedical problems.
Expertise Areas
- Mouse model development and genetic engineering
- Colony management and reproductive technologies
- Preclinical study design and translational modeling
- Clinical genomics and variant interpretation
Key Technologies
- Genetic engineering of animal models
- Patient-derived xenografts (PDX)
- Induced pluripotent stem cell (iPSC) resources
- Spatial transcriptomics
News & Updates
A discovery at The Jackson Laboratory reveals how dysfunctional mitochondria put the immune system on overdrive, leading to severe infections.
Jeff Chuang uses artificial intelligence to analyze gene expression and cell location within tissue samples for better tumor imaging.
Gareth Howell discusses the importance of diverse mouse models and microglia-based genetics in Alzheimer's research.
Interviews with first-generation students in JAX's Summer Student Program about their backgrounds and aspirations.
A summary of 345 research papers and preprints published by JAX in 2024, highlighting key discoveries.
Explores how understanding rare diseases can provide insights into common conditions and improve overall medical research.
A discovery at The Jackson Laboratory reveals how dysfunctional mitochondria put the immune system on overdrive, leading to severe infections.
Jeff Chuang uses artificial intelligence to analyze gene expression and cell location within tissue samples for better tumor imaging.
Gareth Howell discusses the importance of diverse mouse models and microglia-based genetics in Alzheimer's research.
Interviews with first-generation students in JAX's Summer Student Program about their backgrounds and aspirations.
A summary of 345 research papers and preprints published by JAX in 2024, highlighting key discoveries.
Explores how understanding rare diseases can provide insights into common conditions and improve overall medical research.