siTOOLs Biotech


siTOOLs Biotech specializes in gene silencing and RNA research tools, offering products like siPOOLs, riboPOOLs, Phenovault, and RiboCut markers. Their mission is to provide precise, cost-effective, and reliable solutions for gene function analysis, emphasizing simplicity and interpretability in RNAi experiments.

Industries

biotechnology

Nr. of Employees

small (1-50)

siTOOLs Biotech


Products

Complex siRNA pools (30-plex)

Pre-designed or custom siRNA reagent pools containing ~30 distinct siRNAs per target to provide robust gene knockdown with reduced off-target effects.

rRNA depletion probe pools (biotinylated DNA probes)

Complex pools of biotinylated DNA oligonucleotides designed to hybridize to and remove ribosomal RNA from total RNA samples for RNA-Seq and ribosome profiling applications.

High-resolution RPF molecular marker

Molecular size marker to facilitate precise excision of ~30-nt ribosome-protected fragments from preparative denaturing polyacrylamide gels.


Services

High-throughput RNAi screening and data analysis service

Turnkey screening service including experimental execution and data deconvolution to identify gene-function relationships from RNAi screens.

Custom oligonucleotide pool design and quotation service

Custom design and quoting for specialized siRNA pools, rRNA probe combinations and related reagents, with options for custom scales and species adaptation.

Expertise Areas

  • RNA interference (RNAi) and complex siRNA pooling
  • rRNA depletion for RNA-Seq and ribosome profiling
  • Ribosome profiling (Ribo-seq) sample preparation
  • High-throughput RNAi screening and data deconvolution
  • Show More (3)

Key Technologies

  • Complex siRNA pooling
  • Biotinylated DNA probe-based rRNA depletion
  • Ribosome profiling (Ribo-seq)
  • High-throughput screening workflows
  • Show More (4)

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