siTOOLs Biotech


siTOOLs Biotech specializes in gene silencing and RNA research tools, offering products like siPOOLs, riboPOOLs, Phenovault, and RiboCut markers. Their mission is to provide precise, cost-effective, and reliable solutions for gene function analysis, emphasizing simplicity and interpretability in RNAi experiments.

Industries

biotechnology

Nr. of Employees

small (1-50)

siTOOLs Biotech

Lochhamer Str. 29A, Rückgebäude (Building at the end), D-82152 Planegg/Martinsried, Germany


Patents

Alkali metal salt for use in treatment of Varroa destructor mite infestation of honey bees

US-11723366-B2

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Alkali metal salt for use in treatment of varroa destructor mite infestation of honey bees

US-10980238-B2

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High complexity siRNA pools

US-10407677-B2

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Products

Complex siRNA pools (30-plex)

Pre-designed or custom siRNA reagent pools containing ~30 distinct siRNAs per target to provide robust gene knockdown with reduced off-target effects.

rRNA depletion probe pools (biotinylated DNA probes)

Complex pools of biotinylated DNA oligonucleotides designed to hybridize to and remove ribosomal RNA from total RNA samples for RNA-Seq and ribosome profiling applications.

High-resolution RPF molecular marker

Molecular size marker to facilitate precise excision of ~30-nt ribosome-protected fragments from preparative denaturing polyacrylamide gels.


Services

Turnkey screening service including experimental execution and data deconvolution to identify gene-function relationships from RNAi screens.

Custom design and quoting for specialized siRNA pools, rRNA probe combinations and related reagents, with options for custom scales and species adaptation.

Expertise Areas

  • RNA interference (RNAi) and complex siRNA pooling
  • rRNA depletion for RNA-Seq and ribosome profiling
  • Ribosome profiling (Ribo-seq) sample preparation
  • High-throughput RNAi screening and data deconvolution
  • Show More (3)

Key Technologies

  • Complex siRNA pooling
  • Biotinylated DNA probe-based rRNA depletion
  • Ribosome profiling (Ribo-seq)
  • High-throughput screening workflows
  • Show More (4)

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