Singletto


Singletto is a healthcare startup focused on developing and commercializing Oxafence™, an antimicrobial and antibiotic technology that provides ongoing active protection from pathogens. The company applies proven principles of Photodynamic Therapy (PDT) in novel ways to inactivate pathogens, including SARS-CoV-2, through its Antimicrobial Photodynamic Inactivation (aPDI) technology. Singletto's mission is to meet the needs of healthcare, military, industry, and consumers by offering innovative pathogen protection solutions that actively destroy pathogens during product use.

Industries

biotechnology
health-care
medical

Nr. of Employees

small (1-50)

Singletto

Seattle, Washington, United States, North America


Patents

Microbial disinfection for personal protection equipment

US-11925717-B2

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Microbial disinfection for personal protection equipment

US-11458220-B2

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Products

Surgical mask with FDA-cleared antimicrobial photodynamic treatment

A surgical mask product incorporating a light-activated antimicrobial treatment that has obtained U.S. regulatory clearance for virus-inactivation claims.

Methylene Blue (MB) Pre-Treated Masks

Masks pre-treated with the protective dye Methylene Blue (MB) that provide immediate decontamination and ongoing antimicrobial efficacy against viruses including SARS-CoV-2, norovirus, Ebola, Lassa, and Nipah viruses.

ProGear Surgical Mask with Oxafence

FDA-cleared face mask applying Oxafence Active Protection™ technology to mask materials during manufacturing, inactivating 99.9% of tested viruses within 5 minutes on the outer surface, including H1N1 Influenza and OC43 human Coronavirus.

ProGear ASTM L3 Surgical Masks with Oxafence

The ProGear+Oxafence Surgical Masks provide the highest level of ASTM performance plus Oxafence Active Protection technology, which inactivates 99.9% of tested viruses after just five minutes. They feature a four-layer design providing Bacterial and Particulate Filtration Efficiency (BFE & PFE) and Fluid Barrier Protection meeting ASTM Level 3 standards (F2100-23).

Oxafence ProGear ASTM mask

FDA-cleared, virus-inactivating mask using Singletto's patented Oxafence Active Protection technology, designed to inactivate tested viruses.

N95 Respirators

N95 respirators are certified by the U.S. National Institute for Occupational Safety and Health (NIOSH) and are designed to filter at least 95% of specified airborne challenge particles under defined laboratory conditions. They form a tight seal against the wearer’s face and are used primarily for industrial worker safety.

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Services

Partnering and licensing arrangements to integrate light-activated antimicrobial treatments into partner-manufactured PPE, textiles, and consumer products.

Collaborative research and laboratory testing services to evaluate antimicrobial efficacy of treated materials and to develop use-case specific formulations and protocols.

Support for regulatory submissions, product labeling claims, and commercialization pathways for PPE and medical devices incorporating light-activated antimicrobial technologies.

Expertise Areas

  • Antimicrobial photodynamic inactivation (aPDI)
  • PPE decontamination and pre-treatment
  • Textile integration of photosensitizing agents
  • Virology testing and pathogen challenge studies
  • Show More (4)

Key Technologies

  • Photodynamic therapy / antimicrobial photodynamic inactivation
  • Photosensitizing dyes (e.g., methylene blue-based formulations)
  • Singlet oxygen generation and photochemistry
  • Textile impregnation and formulation methods
  • Show More (3)

News & Updates

Singletto collaborates with Kenyan health organizations to evaluate the efficacy of Oxafence technology against Mycobacterium tuberculosis and understand mask-wearing behaviors post-COVID-19.

Supported in the U.S. Defense Advanced Research Projects Agency (DARPA) PPB Program, advancing pathogen protection technologies.

Singletto was featured as a lead story in GeekWire highlighting its innovative technology.

Research published in the American Journal of Infection Control confirms the efficacy of aPDI technology against various pathogens, including SARS-CoV-2, using light-activated dyes like Methylene Blue.

An article discussing the science behind Singletto's Oxafence technology and its applications in healthcare.

WHO updates PPE guidelines to include the use of methylene blue and light for mask decontamination, supported by Singletto's research.

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