Scorpion Biological Services
U.S.-based biologics CDMO providing cGMP manufacturing, integrated bioanalytical testing, and process development for protein modalities, including mammalian, microbial and cell therapy products. Operates a clinical-scale facility in San Antonio, Texas with segregated mammalian and microbial manufacturing areas and on-site analytical and process development laboratories.
Industries
Nr. of Employees
small (1-50)
Scorpion Biological Services
1305 East Houston Street, San Antonio, TX 78205, USA
Services
Clinical-scale cGMP production services in segregated mammalian and microbial cleanrooms with capabilities for upstream, downstream and fill/finish support.
Upstream process optimization, scale-up from miniaturized reactors to 500 L single-use bioreactors, cell harvest and downstream integration.
Strain development, batch and fed-batch fermentation, plasmid DNA production and downstream plasmid/protein recovery using 50 L and 200 L fermentors.
Development and optimization of recovery and purification processes for recombinant proteins, inclusion-body refolding, and cell therapy exosomal products.
Design and execution of cell-based assays, immunoassays, qPCR, ELISA, ELISpot, multiplex assays and flow cytometry for pre-clinical and clinical programs.
cGMP lot release testing, stability study design and execution under ICH guidelines, validated storage and continuous monitoring.
Clinical-scale cGMP production services in segregated mammalian and microbial cleanrooms with capabilities for upstream, downstream and fill/finish support.
Upstream process optimization, scale-up from miniaturized reactors to 500 L single-use bioreactors, cell harvest and downstream integration.
Strain development, batch and fed-batch fermentation, plasmid DNA production and downstream plasmid/protein recovery using 50 L and 200 L fermentors.
Development and optimization of recovery and purification processes for recombinant proteins, inclusion-body refolding, and cell therapy exosomal products.
Design and execution of cell-based assays, immunoassays, qPCR, ELISA, ELISpot, multiplex assays and flow cytometry for pre-clinical and clinical programs.
cGMP lot release testing, stability study design and execution under ICH guidelines, validated storage and continuous monitoring.
Expertise Areas
- Clinical trial sample analysis and GLP support
- Biomanufacturing for mammalian and microbial biologics
- Cell therapy process development and manufacturing
- Downstream purification and protein recovery
Key Technologies
- Single-use stirred-tank bioreactors (50–500 L)
- Benchtop single-use / miniaturized bioreactors
- qPCR / quantitative PCR
- HPLC and chromatographic methods