Rybodyn


RyboDyn is a pioneering immunotherapy developer focused on unlocking the dark proteome using proprietary RyboCypher™ technology. They aim to transform hidden biological signals into breakthrough therapies, redefining patient care through next-generation immunotherapies. Their mission is to turn the secrets of the dark genome into actionable insights and first-in-class immunotherapies that revolutionize healthcare.

Industries

biotechnology
medical
pharmaceutical
therapeutics

Nr. of Employees

small (1-50)

Rybodyn

10935 Alexandria Way, Suite 204, San Diego, CA 92121


Products

Sequencing and AI proteogenomic discovery platform

Integrated platform that combines high-resolution RNA sequencing with machine learning models and curated proteomic datasets to detect cryptic RNAs and predict encoded proteins for target discovery.

Antibody-based immunotherapy candidates

Preclinical antibody drug candidates derived from discovered disease-specific targets designed for high specificity and reduced off-target effects, intended for advancement toward clinical development.


Services

Discovery and experimental validation of disease-specific peptide and cell-surface targets derived from non-canonical transcripts, leveraging sequencing, proteomics, and clinical repository correlation.

Partnership-driven projects that integrate discovery outputs with clinical tumor banks and metadata to accelerate translation of targets into therapeutic programs.

Expertise Areas

  • Dark proteome and dark transcriptome discovery
  • Proteogenomics
  • AI-driven target identification
  • Antibody-based immunotherapy development
  • Show More (3)

Key Technologies

  • High-resolution RNA sequencing
  • Proteogenomic machine learning models
  • Proprietary transcriptomic and proteomic databases
  • Proteomic discovery workflows (peptide detection)
  • Show More (2)

News & Updates

RyboDyn's collaboration with Lilly aims to advance dark proteome targets into first-in-class therapies.

RyboDyn has expanded its collaboration with Moffitt Cancer Center to validate and develop dark targets for cancer immunotherapy.

RyboDyn announced the discovery of a cryptic human proteome and secured $4 million in pre-seed funding.


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