Protean
Protean Ltd. is a certified contract research company specializing in the research and development of pathogen diagnostics and recombinant proteins. With over 25 years of international experience, they focus on innovative solutions in biotechnology, providing high-quality products and services including recombinant proteins, molecular biology reagents, and diagnostic kits. Their mission is to utilize advanced technologies to create novel proteins with diverse properties, investing heavily in R&D to stay at the forefront of biotechnology.
Industries
Nr. of Employees
small (1-50)
Protean
Ceske Budejovice, Jihocesky kraj, Czech Republic, Europe
Products
TEV protease (His6) — recombinant protease for tag removal
Genetically modified TEV protease with His6 tag for cleavage of fusion protein tags; described activity, buffer and temperature recommendations provided.
Cold-adapted protease variant (cold-active protease)
Engineered cold-adapted protease variant offering higher activity and thermal stability at low temperatures for tag cleavage and processing at ~6°C.
FRET protease activity assay kit
FRET-based kit for measuring protease activity designed for easy and precise quality control of protease preparations.
FRET-based protease substrates
Panel of FRET-labelled peptide substrates optimized for various proteases and compatible with high-throughput screening.
Reverse transcriptase optimized for RT-LAMP (thermostable RT)
Thermostable reverse transcriptase optimized genetically for cDNA synthesis and one-step isothermal amplification workflows.
Thermostable strand-displacing DNA polymerase (BstI large fragment)
Large-fragment strand-displacing DNA polymerase suitable for isothermal amplifications (LAMP), whole genome amplification and sequencing of GC-rich templates.
TEV protease (His6) — recombinant protease for tag removal
Genetically modified TEV protease with His6 tag for cleavage of fusion protein tags; described activity, buffer and temperature recommendations provided.
Cold-adapted protease variant (cold-active protease)
Engineered cold-adapted protease variant offering higher activity and thermal stability at low temperatures for tag cleavage and processing at ~6°C.
FRET protease activity assay kit
FRET-based kit for measuring protease activity designed for easy and precise quality control of protease preparations.
FRET-based protease substrates
Panel of FRET-labelled peptide substrates optimized for various proteases and compatible with high-throughput screening.
Reverse transcriptase optimized for RT-LAMP (thermostable RT)
Thermostable reverse transcriptase optimized genetically for cDNA synthesis and one-step isothermal amplification workflows.
Thermostable strand-displacing DNA polymerase (BstI large fragment)
Large-fragment strand-displacing DNA polymerase suitable for isothermal amplifications (LAMP), whole genome amplification and sequencing of GC-rich templates.
Services
Custom protein expression service
Subcloning, sequence optimisation, expression and purification of recombinant proteins with rapid turnaround and delivery of highly pure, biologically active proteins.
RT-LAMP diagnostics development and testing
Development, kit assembly and testing of isothermal amplification diagnostics suitable for field and point-of-care use, including visual and mobile-device readable outputs.
Tick-borne pathogen analysis
Analytical testing of tick samples for presence of tick-borne pathogens performed directly from collected ticks.
DNA analysis / genetic predisposition testing (through separate portal)
Genetic predisposition and DNA analysis services offered via an affiliated portal for consumer and clinical testing.
Contract research for IVD development
Research and development services focused on pathogen diagnostics and recombinant antigen/enzyme development for IVD products.
Employee testing programs (SARS-CoV-2)
Provision of preventive SARS-CoV-2 testing solutions for employers, including self-collection options and laboratory testing.
Custom protein expression service
Subcloning, sequence optimisation, expression and purification of recombinant proteins with rapid turnaround and delivery of highly pure, biologically active proteins.
RT-LAMP diagnostics development and testing
Development, kit assembly and testing of isothermal amplification diagnostics suitable for field and point-of-care use, including visual and mobile-device readable outputs.
Tick-borne pathogen analysis
Analytical testing of tick samples for presence of tick-borne pathogens performed directly from collected ticks.
DNA analysis / genetic predisposition testing (through separate portal)
Genetic predisposition and DNA analysis services offered via an affiliated portal for consumer and clinical testing.
Contract research for IVD development
Research and development services focused on pathogen diagnostics and recombinant antigen/enzyme development for IVD products.
Employee testing programs (SARS-CoV-2)
Provision of preventive SARS-CoV-2 testing solutions for employers, including self-collection options and laboratory testing.
Expertise Areas
- Recombinant protein production
- Enzyme engineering and formulation
- Isothermal diagnostic assay development (LAMP/RT-LAMP)
- Molecular biology reagent manufacturing
Key Technologies
- Isothermal amplification (LAMP/RT-LAMP)
- Strand-displacing DNA polymerases
- Thermostable DNA ligases
- Nonspecific nuclease enzymes