Premas Biotech Pvt, Ltd.
Premas Biotech is dedicated to accelerating drug development through innovative technology platforms and a team of over 150 scientists and managers. Founded in 2005, the company has developed over 650 molecules and focuses on transforming drug discovery, vaccine development, and biotherapeutics. It collaborates globally to provide quality products and solutions for pharmaceutical and biotech companies, emphasizing speed, security, and cost-effectiveness. The company fosters an inclusive and innovative culture, with a focus on teamwork, learning, and long-term partnerships.
Industries
Nr. of Employees
medium (51-250)
Premas Biotech Pvt, Ltd.
Gurgaon, Haryana, India, Asia
Products
Recombinant diagnostic antigens
Purified recombinant viral and other antigens produced in yeast or bacterial hosts and supplied for research, ELISA and lateral-flow diagnostics.
Virus-like particle (VLP) vaccine candidate (preclinical)
Multi-antigen VLP vaccine candidate developed for oral and scalable delivery formats, progressed through preclinical evaluation.
Naive human scFv phage-display library
Large, diverse naive human single-chain variable fragment phage-display library available for antibody lead discovery.
Recombinant proteins and enzymes for alternative-food applications
Production of recombinant proteins, enzymes and ingredient biomolecules for alternative-food applications with strain development, process development, pilot and bulk manufacturing.
Recombinant diagnostic antigens
Purified recombinant viral and other antigens produced in yeast or bacterial hosts and supplied for research, ELISA and lateral-flow diagnostics.
Virus-like particle (VLP) vaccine candidate (preclinical)
Multi-antigen VLP vaccine candidate developed for oral and scalable delivery formats, progressed through preclinical evaluation.
Naive human scFv phage-display library
Large, diverse naive human single-chain variable fragment phage-display library available for antibody lead discovery.
Recombinant proteins and enzymes for alternative-food applications
Production of recombinant proteins, enzymes and ingredient biomolecules for alternative-food applications with strain development, process development, pilot and bulk manufacturing.
Services
Cell line and strain development
Development and optimization of host strains and expression constructs for microbial, yeast and mammalian systems, including clone screening, vector selection and secretion/periplasmic expression strategies.
Scouting and feasibility assessment
Early-stage evaluation services to identify expression strategies, host options and project feasibility prior to full development.
Process development (upstream and downstream)
Comprehensive process development from shake flasks to pilot and commercial-scale bioreactors including media/feed optimization, clarification, chromatography, concentration, refolding and formulation development.
Scale-up and GMP-capable manufacturing
GMP-capable scale-up and manufacturing services, including technology transfer to contract manufacturers and continuous/semi-continuous process operation for gram-to-kilogram supply.
Analytical development and functional assays
Analytical and bioanalytical assay development for identity, purity, potency and stability; execution of ELISA, neutralization assays, ADCC/CDC, HPLC, SDS-PAGE, MS and other orthogonal methods in support of development programs.
Cell line and strain development
Development and optimization of host strains and expression constructs for microbial, yeast and mammalian systems, including clone screening, vector selection and secretion/periplasmic expression strategies.
Scouting and feasibility assessment
Early-stage evaluation services to identify expression strategies, host options and project feasibility prior to full development.
Process development (upstream and downstream)
Comprehensive process development from shake flasks to pilot and commercial-scale bioreactors including media/feed optimization, clarification, chromatography, concentration, refolding and formulation development.
Scale-up and GMP-capable manufacturing
GMP-capable scale-up and manufacturing services, including technology transfer to contract manufacturers and continuous/semi-continuous process operation for gram-to-kilogram supply.
Analytical development and functional assays
Analytical and bioanalytical assay development for identity, purity, potency and stability; execution of ELISA, neutralization assays, ADCC/CDC, HPLC, SDS-PAGE, MS and other orthogonal methods in support of development programs.
Expertise Areas
- Protein biologics and antibody development
- Vaccine development (subunit, conjugate, VLP)
- Host strain engineering and cell line development
- Upstream and downstream bioprocess development and scale-up
Key Technologies
- Yeast expression systems (Pichia, Saccharomyces)
- Bacterial expression systems (E. coli, Bacillus)
- Mammalian expression systems (CHO, HEK)
- Phage-display scFv libraries