Portal Instruments
Portal Instruments is dedicated to revolutionizing drug delivery by developing innovative, needle-free, fast, and connected devices. Their mission is to improve the patient experience with modern, safe, and sustainable solutions, aiming to redefine what it means to self-inject and to become the standard in drug delivery technology.
Industries
Nr. of Employees
small (1-50)
Portal Instruments
Cambridge, Massachusetts, United States, North America
Products
Reusable electromechanical needle-free jet injector platform
Handheld electromechanical jet injector designed to deliver pre-filled biologic formulations without a needle via a narrow high-velocity fluid jet; intended for rapid subcutaneous administration and connected adherence monitoring.
Reusable electromechanical needle-based injector compatible with standard primary containers
Electronic reusable injector designed to work with multiple standard primary containers (e.g., 1 mL and larger pre-filled syringes and cartridges), offering precise control of injection duration and capability to handle a range of viscosities and volumes.
Single-use pre-filled cartridge / primary container
Disposable cartridges designed for pre-filling with biologics and integration into jet- or injector-based delivery systems; engineered for standard fill/finish lines and available in silicone and silicone-free fluid-path variants.
Reusable electromechanical needle-free jet injector platform
Handheld electromechanical jet injector designed to deliver pre-filled biologic formulations without a needle via a narrow high-velocity fluid jet; intended for rapid subcutaneous administration and connected adherence monitoring.
Reusable electromechanical needle-based injector compatible with standard primary containers
Electronic reusable injector designed to work with multiple standard primary containers (e.g., 1 mL and larger pre-filled syringes and cartridges), offering precise control of injection duration and capability to handle a range of viscosities and volumes.
Single-use pre-filled cartridge / primary container
Disposable cartridges designed for pre-filling with biologics and integration into jet- or injector-based delivery systems; engineered for standard fill/finish lines and available in silicone and silicone-free fluid-path variants.
Services
Drug-device partnership and integration
Collaborative programs with biopharma partners to integrate therapeutic formulations with reusable injectors and single-use cartridges, including feasibility, design transfer, and lifecycle strategy.
Manufacturing integration and supplier qualification
Support for selecting and integrating contract manufacturers and suppliers for cartridge production and injector assembly, leveraging pharma-accepted vendors to enable scale-up.
Clinical development support for delivery devices
Design and execution support for clinical studies assessing device safety, user preference, and pain outcomes, including feasibility studies for larger-volume injections.
Software verification & validation and regulatory support
Software lifecycle services including requirements generation, test development and execution, documentation for software qualification, and alignment with ISO 14971 and IEC 62304 risk and safety standards.
Drug-device partnership and integration
Collaborative programs with biopharma partners to integrate therapeutic formulations with reusable injectors and single-use cartridges, including feasibility, design transfer, and lifecycle strategy.
Manufacturing integration and supplier qualification
Support for selecting and integrating contract manufacturers and suppliers for cartridge production and injector assembly, leveraging pharma-accepted vendors to enable scale-up.
Clinical development support for delivery devices
Design and execution support for clinical studies assessing device safety, user preference, and pain outcomes, including feasibility studies for larger-volume injections.
Software verification & validation and regulatory support
Software lifecycle services including requirements generation, test development and execution, documentation for software qualification, and alignment with ISO 14971 and IEC 62304 risk and safety standards.
Expertise Areas
- Needle-free injection systems
- Reusable electromechanical injector development
- Primary container and cartridge engineering for fill-finish
- Clinical trial design and execution for delivery devices
Key Technologies
- Electromechanical linear actuator-driven jet injection
- High-speed jet injection (sub-second delivery)
- Disposable pre-filled cartridge compatible with fill-finish lines
- Nozzle microgeometry and fluid-path optimization