Method and device for delivering subcutaneous dose through multiple injections
Inventors
Anquetil, Patrick Armand • Hunter, Ian
Assignees
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Publication Number
US-12064602-B2
Publication Date
2024-08-20
Expiration Date
Abstract
A device for administering needle-free subcutaneous treatment to a patient comprises an actuator configured to deliver a plurality of volumes of a treatment at a plurality of locations on a body of the patient; at least one imaging device configured to detect a movement of the needle-free device from a first location on the body of the patient to a second location on the body of the patient; and a processor configured to determine the second location on the body of the device relative to the first location from the movement of the needle-free device relative to the first location on the body, the processor further configured to determine a volume of the plurality of volumes of the treatment to deliver to the body of the patient at the second location.
Core Innovation
The disclosed invention relates to a needle-free injector system/device for administering needle-free treatment to a patient by controllably injecting a volume of treatment through a nozzle at one or more depths below a particular treatment site. The injector includes an actuator and at least one sensor configured to determine a location of the device or nozzle relative to the particular treatment site. A processor obtains information from the actuator indicative of the depth to which the treatment was delivered and controls the depth of injection to vertically stack a delivery of the treatment to a treatment site within tissue layers of the patient.
The system determines a device/nozzle position relative to a treatment site using sensors that track movement, including an accelerometer, gyroscope, and barometric sensor. An imaging sensor such as a camera and/or a sonogram can be used to determine the nozzle/device position. Based on information indicative of delivery depth and the volume delivered, the processor determines a treatment volume to deliver at a new location and controllably causes delivery or disables the actuator when appropriate.
The disclosed system supports depth categories including intradermal, subdermal, and intramuscular delivery, and stores injection history and delivered amounts as a two-dimensional array representation or a three-dimensional array representation. In the three-dimensional array, x/y location corresponds to locations on a treatment grid and z corresponds to depth, enabling vertically stacked delivery within tissue layers. A user interface provides guidance and alerts, including speed/velocity indications and alerts to hold motionless, as well as orientation/tilt indications.
Claims Coverage
The document includes two independent claims. Each independent claim is centered on a needle-free injector that uses sensors to determine device/nozzle location relative to a treatment site and a processor that detects delivery depth and volume to control whether to deliver a second volume at a second treatment site or to control delivery depth and vertically stack treatment within tissue layers.
Controllable depth-controlled vertical stacking in tissue layers
An actuator configured to controllably inject a volume of a treatment at one or more depths below a particular treatment site; at least one sensor configured to determine a location of the device relative to the particular treatment site; and a processor configured to obtain information from the actuator indicative of the depth to which the treatment was delivered, and to control a depth of the injection to vertically stack a delivery of the treatment to a treatment site within tissue layers of the patient.
Detect delivery volume and depth to deliver second volume or disable actuator
A nozzle; a reservoir configured to contain the treatment; an actuator configured to controllably inject a volume of the treatment through the nozzle at one or more depths at a particular treatment site; at least one sensor configured to determine a location of the nozzle relative to the particular treatment site; and a processor configured by computer executable code to detect the volume of the treatment delivered and the depth to which the treatment was delivered, and to cause the actuator to one of deliver a second volume to a second particular treatment site of the patient or disable the actuator for a period of time.
Across the independent claims, the core claim scope is directed to needle-free injection with sensor-determined device/nozzle location, processor-detected delivery depth and delivered volume, and processor control to vertically stack delivery within tissue layers or to deliver a second volume at a second treatment site or disable the actuator for a period of time.
Stated Advantages
Enables controlling injection depth to vertically stack a delivery within tissue layers of the patient.
Supports delivering to multiple treatment locations and one or more depths based on detected delivered volume and depth.
Provides actuator disabling for a period of time based on detected delivered volume and depth.
Provides user-interface guidance including speed/velocity indications and hold motionless alerts, as well as orientation/tilt indications.
Documented Applications
Administering a subcutaneous treatment dose via multiple injections across body-surface locations using a needle-free injector that tracks movement and controls injection depth.
Depth-relevant administration for subdermal, intradermal, or intramuscular treatment site categories with vertically stacked delivery within tissue layers.
Recording and representing injection history and delivered amounts using 2D or 3D array representations with depth as a z-axis for delivered volumes across locations on a treatment grid.
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