Pharmathen
Research-oriented pharmaceutical developer and manufacturer providing API and finished-dose R&D, formulation development, analytical services, regulatory support and GMP pilot/commercial manufacturing. Operates GLP/GMP-compliant R&D and manufacturing capabilities, collaborates with academic partners on polymeric and continuous-flow synthesis projects, and supports product lifecycle activities including pharmacovigilance and dossier preparation.
Industries
Nr. of Employees
large (251-1000)
Pharmathen
44 Kifissias Ave., 15125 Marousi, Attica, Greece
Patents
Pediatric powder for oral suspension containing antiviral agent and method for the preparation thereof
US-12458645-B2
View DetailsPediatric powder for oral suspension containing antiviral agent and method for the preparation thereof
US-12453732-B2
View DetailsPediatric powder for oral suspension containing antiviral agent and method for the preparation thereof
US-11969429-B2
View DetailsWater dispersible mini-tablets comprising Enalapril for treatment of hypertension in a pediatric population and method of preparation thereof
US-11318114-B2
View DetailsOrodispersible film composition comprising enalapril for the treatment of hypertension in a pediatric population
US-11154585-B2
View Details
Pediatric powder for oral suspension containing antiviral agent and method for the preparation thereof
US-12458645-B2
View DetailsPediatric powder for oral suspension containing antiviral agent and method for the preparation thereof
US-12453732-B2
View DetailsPediatric powder for oral suspension containing antiviral agent and method for the preparation thereof
US-11969429-B2
View DetailsWater dispersible mini-tablets comprising Enalapril for treatment of hypertension in a pediatric population and method of preparation thereof
US-11318114-B2
View DetailsOrodispersible film composition comprising enalapril for the treatment of hypertension in a pediatric population
US-11154585-B2
View DetailsProducts
Injectable self-healing stimuli-responsive hydrogels (pilot)
Injectable polypeptidic/hybrid hydrogels designed to be stimuli-responsive (pH/temperature) for local and directional release of anticancer drugs; prepared at pilot GMP quantities for preclinical evaluation.
Nanoparticle and microsphere formulations (pilot)
Micro- and nanoscale carriers for targeted or sustained drug release, developed for oncology and neurological indications with pilot production and characterization.
Injectable self-healing stimuli-responsive hydrogels (pilot)
Injectable polypeptidic/hybrid hydrogels designed to be stimuli-responsive (pH/temperature) for local and directional release of anticancer drugs; prepared at pilot GMP quantities for preclinical evaluation.
Nanoparticle and microsphere formulations (pilot)
Micro- and nanoscale carriers for targeted or sustained drug release, developed for oncology and neurological indications with pilot production and characterization.
Services
Development of synthetic routes, impurity control, analytical method development and pilot/commercial API production.
R&D and pilot development for modified-release oral systems, parenteral long-acting injectables and ophthalmic formulations, with technology transfer to manufacturing.
Synthesis of specialized polymers and pilot formulation of hydrogels, nanoparticles and microspheres, including encapsulation workflows for hydrophilic and hydrophobic drugs.
Comprehensive analytical services including method development/validation, compendial testing, stability studies and GMP batch release testing for APIs and finished products.
Toxicology, toxicokinetic, efficacy and PK studies in animal models to support selection of lead formulations and regulatory filings.
Strategic regulatory planning, CTD/eCTD dossier preparation, medical writing, responses to authorities and lifecycle management support.
Development of synthetic routes, impurity control, analytical method development and pilot/commercial API production.
R&D and pilot development for modified-release oral systems, parenteral long-acting injectables and ophthalmic formulations, with technology transfer to manufacturing.
Synthesis of specialized polymers and pilot formulation of hydrogels, nanoparticles and microspheres, including encapsulation workflows for hydrophilic and hydrophobic drugs.
Comprehensive analytical services including method development/validation, compendial testing, stability studies and GMP batch release testing for APIs and finished products.
Toxicology, toxicokinetic, efficacy and PK studies in animal models to support selection of lead formulations and regulatory filings.
Strategic regulatory planning, CTD/eCTD dossier preparation, medical writing, responses to authorities and lifecycle management support.
Expertise Areas
- Formulation development for oral, parenteral and ophthalmic products
- API process development and scale-up
- Polymer-based delivery systems and hydrogels
- Nanoparticle and microsphere drug carriers
Key Technologies
- Continuous flow chemistry
- Polypeptidic and block copolymer synthesis
- Hydrogel (injectable, self-healing, stimuli-responsive) platforms
- Nanoparticle and microsphere encapsulation
News & Updates
Participation in a funded research project developing injectable, stimuli-responsive hydrogels and pilot GMP production for targeted delivery of chemotherapeutics.
Participation in an interdisciplinary project developing polymeric carriers, nanoparticles and patches for targeted delivery in neurodegenerative disease and cancer, with pilot encapsulation and preclinical evaluation.
Patent application filed for injectable pH-responsive polypeptidic hydrogel technology (national patent application referenced).
Completed regulatory inspections and obtained marketing authorizations for long-acting injectable products in multiple territories.
Multiple national and international awards and recognition for R&D investment and innovation.
Participation in a funded research project developing injectable, stimuli-responsive hydrogels and pilot GMP production for targeted delivery of chemotherapeutics.
Participation in an interdisciplinary project developing polymeric carriers, nanoparticles and patches for targeted delivery in neurodegenerative disease and cancer, with pilot encapsulation and preclinical evaluation.
Patent application filed for injectable pH-responsive polypeptidic hydrogel technology (national patent application referenced).
Completed regulatory inspections and obtained marketing authorizations for long-acting injectable products in multiple territories.
Multiple national and international awards and recognition for R&D investment and innovation.