OBI Pharma, Inc


OBI Pharma is a global clinical stage oncology company dedicated to developing innovative cancer therapies, including antibody-drug conjugates (ADCs) and active immunotherapies. With a focus on unmet medical needs, the company advances next-generation technologies and collaborates globally to bring first-in-class and best-in-class drugs to market, aiming to improve patient outcomes and quality of life.

Industries

biotechnology
pharmaceutical

Nr. of Employees

small (1-50)

OBI Pharma, Inc

6F., No.508, Sec. 7, Zhongxiao E. Rd., Nangang Dist., Taipei City, Taiwan


Patents

CRM197 protein expression

US-12234266-B2

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Saponin adjuvant and evaluation method thereof

US-12221461-B2

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Conjugated biological molecules, pharmaceutical compositions and methods

US-12090212-B2

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Compositions of a carbohydrate vaccine for inducing immune responses and uses thereof in cancer treatment

US-12053514-B2

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Antibodies, pharmaceutical compositions and methods

US-11833223-B2

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Methods of making high enantioselective secondary alcohols

US-11773118-B2

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Products

Clinical-stage ADC therapeutic candidates (multiple targets)

A portfolio of clinical and preclinical ADC candidates targeting tumor antigens (including TROP2, Nectin4, HER2 and dual-antigen formats) developed using site-specific conjugation and linker technologies.

Enzyme-activated prodrug candidates

Prodrug molecules designed to be activated by tumor-associated enzymes to selectively release cytotoxic agents within cancer cells.


Services

Licensing and transferring enabling ADC technologies and know-how to partners, including master services and marketing agreements to expand regional adoption of conjugation and glycan production capabilities.

Execution of multi-phase clinical programs and preparation of regulatory filings (IND/CTA) to advance oncology candidates through clinical development.

Out-licensing of therapeutic candidates and support for commercialization strategies including market partnerships and transfer of product rights to affiliates or partners.

Expertise Areas

  • Antibody-drug conjugate development
  • Glycoscience and glycan engineering
  • Linker and conjugation chemistry
  • Bispecific and multi‑payload ADC engineering
  • Show More (6)

Key Technologies

  • Glycan-based site-specific conjugation
  • Cysteine-selective conjugation chemistry
  • Hydrophilic linker chemistry
  • Endoglycosidase-mediated transglycosylation
  • Show More (6)

News & Updates

OBI Pharma (4174.TWO) convened its 2025 Annual General Shareholders’ Meeting and announced a strategic focus on ADCs, out-licensing products and platform technologies to drive global collaboration.

OBI Pharma participated in the 4th World ADC Asia Summit with presentations and posters showcasing its latest research achievements in ADC technology.

OBI Pharma entered into a Master Services Agreement with TegMine Therapeutics to collaborate on ADC technologies using GlycOBI® and TegMiner™.

OBI Pharma debuted its ThiOBI® platform and HYPrOBI™ linker technology at the AACR Annual Meeting, demonstrating advanced ADC development capabilities.

OBI Pharma was recognized for its promising immunotherapy pipeline, including TROP2 ADC research.

Research on OBI-992, a TROP2-targeted ADC, demonstrating resistance profiles and antitumor activity.

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