NovaHep
NovaHep is a biotechnology company pioneering in regenerative medicine, developing stem cell technology for generating human tissues for reconstructive surgery, toxicity, and biocompatibility studies. The company's mission is to deliver life-changing impact to patients by providing 'Vessels for LIFE' and to benefit hospitals, healthcare providers, and society globally through advanced stem cell technology and tissue engineering. Additionally, NovaHep offers a range of recombinant vectors and plasmids for research and therapeutic development, including gene delivery systems and viral vectors for various applications.
Industries
Nr. of Employees
small (1-50)
Patents
Products
Personalized tissue-engineered vascular graft (autologous cell–seeded decellularized scaffold)
An individualized vascular graft created by recellularizing a decellularized donor vessel extracellular matrix with a patient’s own stem/progenitor cells for reconstructive and vascular surgery.
Catalog of laboratory reagents, genetic constructs, viral vectors and expression kits
A catalog of molecular biology reagents and genetic constructs including plasmid expression constructs, AAV plasmids, retroviral/lentiviral vectors, pre-made viral particles, shRNA/miRNA constructs, baculovirus expression kits, recombinant proteins, antibodies, assay kits (PCR, ELISA, chemiluminescent) and assay control reagents, provided via distributor channels.
Personalized tissue-engineered vascular graft (autologous cell–seeded decellularized scaffold)
An individualized vascular graft created by recellularizing a decellularized donor vessel extracellular matrix with a patient’s own stem/progenitor cells for reconstructive and vascular surgery.
Catalog of laboratory reagents, genetic constructs, viral vectors and expression kits
A catalog of molecular biology reagents and genetic constructs including plasmid expression constructs, AAV plasmids, retroviral/lentiviral vectors, pre-made viral particles, shRNA/miRNA constructs, baculovirus expression kits, recombinant proteins, antibodies, assay kits (PCR, ELISA, chemiluminescent) and assay control reagents, provided via distributor channels.
Services
Surgical transplantation of tissue-engineered vascular grafts produced by recellularizing decellularized scaffolds with autologous cells, with documented clinical cases.
In-house process development services to refine recellularization procedures and media production for regulatory-compliant manufacturing and scale-up readiness.
Sourcing and distribution of a catalog of plasmid constructs, AAV plasmids, pre-made viral particles, retroviral/lentiviral vectors, shRNA/miRNA constructs, recombinant proteins, antibodies, assay kits (PCR, ELISA, enzymatic) and assay controls via distributor and online channels.
Surgical transplantation of tissue-engineered vascular grafts produced by recellularizing decellularized scaffolds with autologous cells, with documented clinical cases.
In-house process development services to refine recellularization procedures and media production for regulatory-compliant manufacturing and scale-up readiness.
Sourcing and distribution of a catalog of plasmid constructs, AAV plasmids, pre-made viral particles, retroviral/lentiviral vectors, shRNA/miRNA constructs, recombinant proteins, antibodies, assay kits (PCR, ELISA, enzymatic) and assay controls via distributor and online channels.
Expertise Areas
- Tissue engineering for vascular replacement
- Regenerative medicine and autologous cell therapy development
- GMP-capable bioprocess and manufacturing scale-up for cell-based products
- Clinical transplantation and surgical deployment of engineered tissues
Key Technologies
- Decellularized extracellular matrix scaffolds
- Peripheral blood-derived stem/progenitor cell isolation
- Lattice light-sheet microscopy
- Adaptive optics for deep tissue imaging
News & Updates
An article discussing mechanisms of immune evasion in renal cell carcinoma, highlighting recent research and potential therapeutic targets.
De- and recellularization of a blood vessel using bone-marrow stem cells
Successful de- and recellularization of a blood vessel (a vein without valves) using bone-marrow stem cells.
Development of solutions and media for de- and recellularization
Development of solutions and media needed to facilitate the de- and recellularization process.
Adaptation of de-/recellularization technique to veins with valves
Adaptation of the de-/recellularization technique to veins with valves.
Development of a refined procedure for recellularizing blood vessels for scale-up in GMP environment
Development of a refined procedure for recellularizing blood vessels, now ready for scale-up in a regulatory correct environment (GMP).
Development of a technique for isolation of stem cells from peripheral blood
Development of a technique for isolation of stem cells from peripheral whole blood.
An article discussing mechanisms of immune evasion in renal cell carcinoma, highlighting recent research and potential therapeutic targets.
De- and recellularization of a blood vessel using bone-marrow stem cells
Successful de- and recellularization of a blood vessel (a vein without valves) using bone-marrow stem cells.
Development of solutions and media for de- and recellularization
Development of solutions and media needed to facilitate the de- and recellularization process.
Adaptation of de-/recellularization technique to veins with valves
Adaptation of the de-/recellularization technique to veins with valves.
Development of a refined procedure for recellularizing blood vessels for scale-up in GMP environment
Development of a refined procedure for recellularizing blood vessels, now ready for scale-up in a regulatory correct environment (GMP).
Development of a technique for isolation of stem cells from peripheral blood
Development of a technique for isolation of stem cells from peripheral whole blood.