NorthLinks Bio
Clinical-stage biopharmaceutical company developing a glycan-targeted, intranasal prophylactic designed to block respiratory virus attachment at the nasal mucosa. Lead investigational candidate completed Phase 1 and a Phase 2 controlled human influenza challenge study with reported reductions in symptomatic influenza and comparable safety to placebo. Platform is based on engineered multivalent carbohydrate-binding modules intended for scalable recombinant manufacture and broad activity across multiple respiratory viruses.
Industries
Nr. of Employees
small (1-50)
Patents
Products
HEX17
Investigational intranasal multivalent glycan-binding protein developed as a broad-spectrum antiviral prophylactic intended to block respiratory virus attachment at the nasal mucosa.
HEX17
Investigational intranasal multivalent glycan-binding protein developed as a broad-spectrum antiviral prophylactic intended to block respiratory virus attachment at the nasal mucosa.
Expertise Areas
- Clinical trial management (including human challenge models)
- Protein engineering and engineered biologics
- Intranasal/respiratory drug delivery
- CMC and scale-up for biologics
Key Technologies
- Multivalent carbohydrate-binding modules (CBMs)
- Recombinant protein expression in E. coli
- Self-assembling trimerization domains
- Intranasal spray delivery
News & Updates
Peer-reviewed Phase II study report describing CHIM results for the investigational intranasal antiviral.
Review/article describing an intranasal glycan-targeted biotherapeutic and its preclinical profile.
Research article on host-receptor targeting using engineered proteins.
Company announced launch with $34 million financing to advance broad-spectrum respiratory antiviral platform.
Peer-reviewed Phase II study report describing CHIM results for the investigational intranasal antiviral.
Review/article describing an intranasal glycan-targeted biotherapeutic and its preclinical profile.
Research article on host-receptor targeting using engineered proteins.
Company announced launch with $34 million financing to advance broad-spectrum respiratory antiviral platform.