InvisiShield Technologies, Ltd.
Pre-clinical-stage biotechnology company developing intranasal preventive therapies to neutralize airborne respiratory viruses at the nasal mucosa. The organization develops a platform that combines a pathogen-binding component, a virus-killing mechanism that activates complement, and a formulation approach to increase nasal retention. Lead development is an intranasal topical preventive intended to provide immediate, short-term protection against SARS-CoV-2, with the platform being applied to influenza and RSV. Headquartered in Emeryville, California.
Industries
N/A
Products
Intranasal COVID-19 preventive spray (lead candidate)
Pre-clinical intranasal topical formulation designed to bind and neutralize SARS-CoV-2 in the nasal cavity, incorporating enhanced mucosal retention and a complement-activating killing mechanism. Demonstrated prevention of infection in cell-based assays and at least 10 hours of protection in mouse challenge studies at the lowest tested dose.
Intranasal COVID-19 preventive spray (lead candidate)
Pre-clinical intranasal topical formulation designed to bind and neutralize SARS-CoV-2 in the nasal cavity, incorporating enhanced mucosal retention and a complement-activating killing mechanism. Demonstrated prevention of infection in cell-based assays and at least 10 hours of protection in mouse challenge studies at the lowest tested dose.
Expertise Areas
- Intranasal drug delivery and mucosal formulations
- Preclinical virology and immunology research
- In vivo infectious disease models (mouse challenge studies)
- In vitro pseudotyped-virus neutralization assays
Key Technologies
- Intranasal drug delivery
- Mucosal adhesion / nasal retention formulations
- Pathogen-binding biologic agents
- Complement activation–based viral neutralization