NeuroDex


NeuroDex is dedicated to enabling precision medicine for neurodegenerative diseases by developing blood-based biomarkers and innovative diagnostic technologies. Their mission is to provide researchers and clinicians with information and tools to improve brain health, focusing on diseases like Parkinson’s, Alzheimer’s, and Lewy body dementia. They leverage extracellular vesicles, exosomes, and advanced blood biomarker technologies to facilitate early diagnosis, monitor treatment response, and support drug development. Their work includes biomarker discovery services, proprietary isolation platforms like ExoSORT, and collaborations with industry and academia to advance neurodegenerative disease research.

Industries

Biotechnology
Health Care
Health Diagnostics
Medical
Biotechnology Research

Nr. of Employees

small (1-50)

NeuroDex

Natick, Massachusetts, United States


Products

Immunoaffinity extracellular vesicle isolation platform

Laboratory platform for antibody-based capture and enrichment of neuron-derived extracellular vesicles from small volumes of plasma or serum for downstream protein and RNA analysis.

Intact extracellular vesicle multiplex immunoassay kit

Bead-indexed multiplex immunoassay for direct capture and semi-quantitative analysis of intact EVs from diluted plasma, enabling multiplex protein detection and co-localization analyses from ~100 µL samples.

Neuron-Derived Exosome Biomarker Discovery Solutions

Advanced biomarker discovery solutions utilizing neuron-derived extracellular vesicle (NDE) panels for precise disease detection, monitoring, and treatment evaluation in neurological disorders.

Biomarker Discovery

Comprehensive biomarker discovery services combining genomics, proteomics, cytokine profiling, flow cytometry, and spatial profiling to identify vital disease indicators, support drug development, and advance personalized medicine.

Biomarker Discovery & Validation

Unbiased discovery of biomarkers for any indication and context of use, including novel discovery, NDE compatibility and verification testing, and proteomic analysis.

Neurodiagnostic Platform

An advanced neurodiagnostic platform built on proprietary neuron-derived extracellular vesicle (NDE) technology, offering comprehensive biomarker panels for disease detection, treatment monitoring, and therapeutic development.

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Services

Contract research services for discovery, assay development, qualification and validation of blood-based biomarkers using EV-targeted isolation and downstream molecular/proteomic analyses; engagement from early research to clinical implementation.

Expertise Areas

  • Extracellular vesicle (EV) isolation and characterization
  • Biomarker discovery and validation for neurology
  • Immunoassay development and multiplexing
  • Proteomics and transcriptomics applied to liquid biopsies
  • Show More (3)

Key Technologies

  • Extracellular vesicle immunoaffinity capture
  • Bead-based multiplex immunoassay for intact EVs
  • Next-generation RNA sequencing (RNA-seq)
  • Quantitative PCR (qPCR)
  • Show More (4)

News & Updates

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