National Institute of Standards and Technology


The U.S. national metrology institute that develops measurement science, reference materials, test methods, standards and calibration services across physical sciences, engineering, cybersecurity, bioscience, and infrastructure. Activities include development of measurement tools and benchmarks, production and distribution of standard reference materials and databases, operation of calibration and testbed facilities, and coordination of standards and evaluation frameworks to support industry, government, and research.

Industries

government
life-science
nanotechnology

Nr. of Employees

Very Large (1000+)

National Institute of Standards and Technology

Gaithersburg, Maryland, United States, North America


Patents

Gradient elution moving boundary electrophoresis for use with complex samples and detection of toxins

US-11479804-B1

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Nanohole array based sensors with various coating and temperature control

US-11035792-B2

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Noncontact resonameter, process for making and use of same

US-10261032-B2

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Phase shift detector process for making and use of same

US-10247814-B2

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Gradient elution isotachophoretic apparatus for separating, purifying, concentrating, quantifying, and/or extracting charged analytes and methods thereof

US-10067088-B2

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Single molecule filter and single molecule electrograph, and process for making and using same

US-10067118-B2

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Products

Mass spectral library and analytical reference databases

Curated spectral and analytical databases used for compound identification and analytical method support.

Standard Reference Materials (SRMs) and research-grade biological materials

Certified reference materials for DNA, RNA, proteins, microbiome matrices and other materials used for calibration, QA/QC and method validation.

Imaging phantoms and clinical imaging calibration products

Physical phantoms and associated measurement protocols for calibrating MRI and other imaging modalities to support clinical imaging QA.

Microbiome reference material

Reference material developed to support gut microbiome research and method harmonization for microbiome measurement.


Services

Laboratory-based calibration, instrument characterization and measurement services to establish traceability and reduce measurement uncertainty.

Provision and distribution of certified reference materials (SRMs) and curated reference databases for analytical, forensic and clinical applications.

Development and dissemination of evaluation frameworks, benchmarks, guidance documents and public testbeds for AI, data tools and cybersecurity practices.

Development and provision of research-grade biological test materials and associated measurement guidance to calibrate and validate diagnostic assays and lab methods.

Testing and measurement services for PPE performance and decontamination validation, and development of standards/testing approaches for vaccine refrigeration and cold storage.

Expertise Areas

  • National metrology and measurement infrastructure
  • Standards and documentary standards development
  • Reference materials for biological and chemical testing
  • AI and machine-learning evaluation and benchmarking
  • Show More (6)

Key Technologies

  • Mass spectrometry and curated spectral libraries
  • Atomic clocks and time/frequency standards
  • Neutron scattering and radiation-based imaging
  • Automated biofoundry workflows
  • Show More (6)

News & Updates

Announcement of a reference material intended to support gut microbiome research and improve comparability of microbiome measurements.

Summary of a NIST researcher presenting on measurement and standards topics at an international healthcare innovation forum.

Release of a standard intended to improve dosage delivery accuracy for radiopharmaceuticals and related therapies.

Blog post explaining how measurement and calibration practices improve clinical outcomes for cancer patients.


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