Molzym
Molzym is a company dedicated to developing innovative solutions for the molecular diagnosis of infectious diseases caused by bacteria and fungi. They manufacture ultra-clean reagents, kits, and automation systems for microbial nucleic acid extraction, human DNA depletion, and pathogen detection using PCR and Next-Generation Sequencing. Their mission is to enable rapid, culture-independent diagnosis of pathogens in clinical and research settings, with a focus on contamination-free, sensitive, and automated solutions.
Industries
Nr. of Employees
small (1-50)
Products
Automated kit for host DNA depletion and microbial DNA isolation (IVD)
IVD kit for automated depletion of host DNA and extraction of bacterial and fungal DNA from a range of human specimens; designed for use with a bench-top robotic extraction instrument and validated for fluids, tissues and swabs.
Bench-top robotic instrument for automated microbial DNA extraction
Instrument for fully automated processing of clinical specimens performing host-depletion steps, vacuum-driven pathogen capture, membrane lysis and DNA purification with flexible throughput (1–12 samples).
Broad-range molecular pathogen diagnosis kit (CE IVD)
CE-marked kit for culture-independent detection of bacterial and fungal pathogens combining pre-analytic enrichment, 16S/18S PCR or real-time PCR and amplicon sequencing for species identification.
Ultra-deep microbiome preparation kit
Kit for microbial DNA enrichment from fluids and tissues with depletion of non-target host DNA to increase sequencing depth in microbiome and metagenome studies (supports small and large volumes).
DNA-free PCR master mixes for 16S amplicon amplification
High-activity amplification mixes manufactured to be free of contaminating microbial DNA, optimized for sensitive amplification of bacterial 16S targets and compatible with downstream library preparation.
Large-volume pathogen DNA extraction add-on kit
Kit module to enable microbial DNA extraction from larger sample volumes (up to 10 ml) to enhance detection sensitivity for low-burden specimens.
Automated kit for host DNA depletion and microbial DNA isolation (IVD)
IVD kit for automated depletion of host DNA and extraction of bacterial and fungal DNA from a range of human specimens; designed for use with a bench-top robotic extraction instrument and validated for fluids, tissues and swabs.
Bench-top robotic instrument for automated microbial DNA extraction
Instrument for fully automated processing of clinical specimens performing host-depletion steps, vacuum-driven pathogen capture, membrane lysis and DNA purification with flexible throughput (1–12 samples).
Broad-range molecular pathogen diagnosis kit (CE IVD)
CE-marked kit for culture-independent detection of bacterial and fungal pathogens combining pre-analytic enrichment, 16S/18S PCR or real-time PCR and amplicon sequencing for species identification.
Ultra-deep microbiome preparation kit
Kit for microbial DNA enrichment from fluids and tissues with depletion of non-target host DNA to increase sequencing depth in microbiome and metagenome studies (supports small and large volumes).
DNA-free PCR master mixes for 16S amplicon amplification
High-activity amplification mixes manufactured to be free of contaminating microbial DNA, optimized for sensitive amplification of bacterial 16S targets and compatible with downstream library preparation.
Large-volume pathogen DNA extraction add-on kit
Kit module to enable microbial DNA extraction from larger sample volumes (up to 10 ml) to enhance detection sensitivity for low-burden specimens.
Services
Mastermix decontamination and purification service
Removal of contaminating microbial nucleic acids from custom or commercial amplification master mixes to enable reliable high-cycle PCR.
Sequence analysis software and database access
Web-based sequence-analysis tool and curated reference sequence collection for identification of bacterial 16S and selected fungal 18S amplicons.
Licensing and collaboration for assay and automation development
Opportunities for collaborative development and licensing of pre-analytic and analytic adaptations including automated DNA isolation.
Technical support, training and documentation
Provision of manuals, application notes, webinars and on-request training to support implementation of molecular diagnostic workflows.
Mastermix decontamination and purification service
Removal of contaminating microbial nucleic acids from custom or commercial amplification master mixes to enable reliable high-cycle PCR.
Sequence analysis software and database access
Web-based sequence-analysis tool and curated reference sequence collection for identification of bacterial 16S and selected fungal 18S amplicons.
Licensing and collaboration for assay and automation development
Opportunities for collaborative development and licensing of pre-analytic and analytic adaptations including automated DNA isolation.
Technical support, training and documentation
Provision of manuals, application notes, webinars and on-request training to support implementation of molecular diagnostic workflows.
Expertise Areas
- Culture-independent molecular pathogen diagnostics
- Host DNA depletion and microbial DNA enrichment
- Automation of pre-analytic and extraction workflows
- Broad-range 16S/18S PCR and Sanger sequencing identification
Key Technologies
- Host DNA depletion by selective host lysis and nuclease digestion
- Automated bench-top robotic DNA extraction (1–12 samples)
- Vacuum-driven pathogen capture and membrane-based DNA purification
- Broad-range 16S/18S rRNA gene PCR and real-time PCR