Medinstill Development LLC
Medinstill Development LLC is dedicated to providing innovative sterile filling, dispensing, and packaging solutions for the pharmaceutical, biotech, healthcare, nutrition, and cosmetic industries. Their technologies focus on increasing safety, efficacy, and reducing contamination risks in liquid and semi-solid product delivery. With a strong emphasis on safety, cost-effectiveness, and regulatory compliance, Medinstill has developed proprietary technologies such as INTACT™ for sterilization, filling, and dispensing, which are used globally in various applications including vaccines, pharmaceuticals, nutrition, and cosmetics. The company holds an extensive patent portfolio and has a fully integrated research, development, and manufacturing capability, including pilot plants and validation laboratories. Their mission is to ensure the highest safety standards for healthcare delivery, especially in hospitals, pandemics, and emergency situations.
Industries
Nr. of Employees
medium (51-250)
Medinstill Development LLC
Medinstill Development LLC, 123 Innovation Drive, New Milford, CT 06776
Products
Modular automated closed-container filler (IMF)
A modular automatic filler that loads, positions, fills by needle piercing of a septum, and unloads closed containers; designed for scalability, minimal moving parts, and operation without isolators.
Portable table-top closed-container filler (Mini-IMF)
A compact, portable filler for small-lot and localized sterile filling applications, designed for field, hospital, laboratory and emergency use.
One-way non-contamination dispensing valve
Elastomeric one-way valve that allows dispensing of solutions, gels, suspensions or creams while preventing ingress of contaminants, enabling preservative-free multi-dose use and metered dosing options.
Multiple-use sterile connectors
Connectors that enable sterile transfers, sampling and connections between containers or equipment multiple times without exposing the fluid path, validated for seal integrity, microbial exclusion and functional performance.
Sterile multiple-dose containers and flexible packaging
Pre-sterilized closed containers (bottles, pouches, tubes, bag-in-box) and flexible packaging systems compatible with septum-based filling and one-way dispensing valves for preservative-free multi-dose applications.
Reusable dispensing systems and rechargeable bags
Integrated reusable dispenser designs and rechargeable bag/valve combinations that allow containers to be refilled or recharged while preserving product sterility across multiple uses.
Modular automated closed-container filler (IMF)
A modular automatic filler that loads, positions, fills by needle piercing of a septum, and unloads closed containers; designed for scalability, minimal moving parts, and operation without isolators.
Portable table-top closed-container filler (Mini-IMF)
A compact, portable filler for small-lot and localized sterile filling applications, designed for field, hospital, laboratory and emergency use.
One-way non-contamination dispensing valve
Elastomeric one-way valve that allows dispensing of solutions, gels, suspensions or creams while preventing ingress of contaminants, enabling preservative-free multi-dose use and metered dosing options.
Multiple-use sterile connectors
Connectors that enable sterile transfers, sampling and connections between containers or equipment multiple times without exposing the fluid path, validated for seal integrity, microbial exclusion and functional performance.
Sterile multiple-dose containers and flexible packaging
Pre-sterilized closed containers (bottles, pouches, tubes, bag-in-box) and flexible packaging systems compatible with septum-based filling and one-way dispensing valves for preservative-free multi-dose applications.
Reusable dispensing systems and rechargeable bags
Integrated reusable dispenser designs and rechargeable bag/valve combinations that allow containers to be refilled or recharged while preserving product sterility across multiple uses.
Services
Pilot plant sterile processing and filling services including UHT processing, homogenization, sterile tank filling, and modular filler operation to produce launch quantities and support scale-up.
Mechanical design and rapid prototyping services including CAD modeling, mold design, SLA printing, CNC machining, and pilot mold fabrication for device development and validation.
In-house microbiology testing (micro-challenge, aerosol/liquid exposure), media fills, and third-party laboratory coordination to validate sterilization, connector/valve performance and filling processes.
Licensing of sterile filling and dispensing technologies and collaboration for implementation in partner manufacturing operations.
Pilot plant sterile processing and filling services including UHT processing, homogenization, sterile tank filling, and modular filler operation to produce launch quantities and support scale-up.
Mechanical design and rapid prototyping services including CAD modeling, mold design, SLA printing, CNC machining, and pilot mold fabrication for device development and validation.
In-house microbiology testing (micro-challenge, aerosol/liquid exposure), media fills, and third-party laboratory coordination to validate sterilization, connector/valve performance and filling processes.
Licensing of sterile filling and dispensing technologies and collaboration for implementation in partner manufacturing operations.
Expertise Areas
- Sterile closed-container filling systems
- Modular automated filling equipment design
- Preservative-free multiple-dose dispensing
- Multiple-use sterile connector design and validation
Key Technologies
- Closed-container needle-based filling
- In-line sterilization (contained sterilant, gamma, e-beam, autoclave)
- Laser resealing of septa
- UV pulse aseptization
News & Updates
Business Wire – August 23, 2022. A strategic partnership to improve vaccine delivery using INTACT™ technology.
Reuters – August 2021. Progress in vaccine bottling using INTACT™ technology.
The Daily Gazette – March 2021. Development of faster vaccine manufacturing methods.
Pharmanews Intelligence – March 2021. Funding to enhance vaccine production and distribution.
Announcement of a global alliance for INTACT™ Technology with Encube Ethicals.
EMA approval of Synflorix™ from GSK Biologicals using INTACT™ technology.
Business Wire – August 23, 2022. A strategic partnership to improve vaccine delivery using INTACT™ technology.
Reuters – August 2021. Progress in vaccine bottling using INTACT™ technology.
The Daily Gazette – March 2021. Development of faster vaccine manufacturing methods.
Pharmanews Intelligence – March 2021. Funding to enhance vaccine production and distribution.
Announcement of a global alliance for INTACT™ Technology with Encube Ethicals.
EMA approval of Synflorix™ from GSK Biologicals using INTACT™ technology.