MBF Therapeutics


Developer of an integrated immune-intelligence platform for animal vaccine research that links standardized in vitro assays, deep immunoprofiling, and in vivo challenge studies to generate longitudinal, machine-learning-ready datasets and train predictive immunology models.

Industries

Biotechnology
Life Science
Oncology
Therapeutics
Veterinary
Biotechnology Research

Nr. of Employees

small (1-50)


Patents

Alphaherpesvirus glycoprotein d-encoding nucleic acid constructs and methods

US-11130787-B2

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Products

Immune intelligence platform for animal vaccine R&D

An integrated experimental and data platform that combines antigen design, deep immunoprofiling, nanoparticle delivery, and ML-ready data curation to support predictive model development and vaccine candidate optimization.

T-Max™ DNA T Cell Vaccine Platform

A proprietary DNA vaccine platform that identifies clinically relevant pathogen antigens and delivers them in proprietary formulations to stimulate durable and potent T cell immune responses, including universal vaccines with cross-protection.

Tmax

A veterinary DNA vaccine platform developed by MBF Therapeutics designed for efficient delivery and enhanced immune response in animals.

COVE-001

A next-generation SARS CoV-2 vaccine candidate developed by MBF Therapeutics focusing on DNA-based vaccines that elicit potent T-cell responses to conserved antigens for broad-spectrum protection.

CaptaVax™ nanoparticle delivery system

A proprietary biodegradable, immunologically inert, non-viral nanoparticle delivery system targeting gene delivery to dendritic and other antigen presenting cells, allowing safe and efficient re-administration.

canine melanoma vaccine

A personalized, alternative strategy for the prevention and treatment of melanoma in dogs, developed through a collaboration between The Wistar Institute and Man’s Best Friend Therapeutics.

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Services

End-to-end vaccine research service that integrates in vitro antigen screening, antigen construct production, nanoparticle formulation, in vivo testing, and standardized metadata capture to generate ML-ready immune datasets.

Expertise Areas

  • Veterinary vaccine development
  • Immunoprofiling and immune-repertoire analysis
  • Preclinical study design and challenge models
  • Antigen discovery and optimization
  • Show More (4)

Key Technologies

  • Machine learning / foundation-model training
  • TCR and BCR repertoire profiling
  • Cytokine and cellular profiling
  • Calcium phosphate nanoparticle delivery
  • Show More (5)

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