Manus Bio, Inc.
Manus Bio Inc. is a leading bioalternatives scale-up platform dedicated to accelerating the commercialization of biologically produced alternatives across food ingredients, agricultural inputs, and industrial materials. The company leverages advanced fermentation technology and synthetic biology to produce sustainable, cost-effective, and reliable natural products, reducing dependence on finite resources and supporting supply chain resilience. Manus collaborates with industry leaders, develops innovative bio-based solutions, and contributes to the growth of the bioeconomy, with a focus on environmental sustainability and market readiness.
Industries
Nr. of Employees
medium (51-250)
Manus Bio, Inc.
Cambridge, Massachusetts, United States, North America
Products
Fermentation-derived citrus flavor ingredient (nootkatone)
A fermentation-produced citrus flavor compound formulated to match natural citrus extracts, produced without agricultural citrus inputs and designed for consistent sensory profile and lower greenhouse gas intensity than plant-derived sources.
Fermentation-derived sweetener ingredients (steviol glycoside analogs)
Microbially produced sweetener molecules that replicate plant-derived sweetener chemistry to provide stable supply and improved cost and sensory outcomes versus traditional extraction.
Environmentally friendly acaricide/tick repellent ingredient
A plant-derived acaricidal compound reproduced via fermentation to enable scalable production for topical consumer products that repel and incapacitate ticks and other insects.
Fermentation-derived artemisinin precursor and semi-synthetic artemisinin production
Production of an artemisinin precursor via fermentation combined with continuous-flow chemical conversion to produce artemisinin and derivatives at scale for antimalarial therapies.
Fermentation-derived citrus flavor ingredient (nootkatone)
A fermentation-produced citrus flavor compound formulated to match natural citrus extracts, produced without agricultural citrus inputs and designed for consistent sensory profile and lower greenhouse gas intensity than plant-derived sources.
Fermentation-derived sweetener ingredients (steviol glycoside analogs)
Microbially produced sweetener molecules that replicate plant-derived sweetener chemistry to provide stable supply and improved cost and sensory outcomes versus traditional extraction.
Environmentally friendly acaricide/tick repellent ingredient
A plant-derived acaricidal compound reproduced via fermentation to enable scalable production for topical consumer products that repel and incapacitate ticks and other insects.
Fermentation-derived artemisinin precursor and semi-synthetic artemisinin production
Production of an artemisinin precursor via fermentation combined with continuous-flow chemical conversion to produce artemisinin and derivatives at scale for antimalarial therapies.
Services
BioAccelerator and scale-readiness programs
Structured programs providing end-to-end support from pathway and strain development through piloting and commercial manufacturing to accelerate partner products to market.
cGMP manufacturing and contract production
On-site, cGMP-capable production services for pharmaceutical intermediates, APIs and high-volume bio-based ingredients integrating fermentation and chemical conversion routes.
Analytical development and quality assurance services
Analytical testing, specification development and QA workflows to support product characterization, batch release and regulatory submissions for bio-based molecules.
Partnership development and co‑development agreements
Co-development and commercialization services that coordinate technical development, supply agreements and commercialization plans with ingredient formulators and commercial partners.
BioAccelerator and scale-readiness programs
Structured programs providing end-to-end support from pathway and strain development through piloting and commercial manufacturing to accelerate partner products to market.
cGMP manufacturing and contract production
On-site, cGMP-capable production services for pharmaceutical intermediates, APIs and high-volume bio-based ingredients integrating fermentation and chemical conversion routes.
Analytical development and quality assurance services
Analytical testing, specification development and QA workflows to support product characterization, batch release and regulatory submissions for bio-based molecules.
Partnership development and co‑development agreements
Co-development and commercialization services that coordinate technical development, supply agreements and commercialization plans with ingredient formulators and commercial partners.
Expertise Areas
- Cell factory and metabolic engineering
- Enzyme engineering and biochemical characterization
- High-throughput automation and screening
- Fermentation scale-up and large-scale biomanufacturing
Key Technologies
- Precision fermentation (pilot to multi-10k L)
- Microbial genome engineering and high-throughput strain construction
- Computational protein design
- Lipid nanodisc and membrane protein assay platforms