Likarda, LLC
Likarda is a biotech company dedicated to transforming the delivery of cell therapies through innovative, customizable hydrogel-based platforms. Their mission is to increase the potency and efficacy of cell therapies by developing advanced encapsulation and delivery technologies, including Core Shell Spherification® (CSS), to protect, target, and enhance therapeutic outcomes. With a culture emphasizing diversity, inclusion, and scientific excellence, Likarda aims to provide sustainable solutions for treating chronic and fatal diseases in both human and animal health.
Industries
Nr. of Employees
small (1-50)
Likarda, LLC
Cambridge, Massachusetts, United States, North America
Products
Hydrogel microbead encapsulation platform
A platform technology to encapsulate cells, cell clusters, peptides, antibodies, or scaffolds in tunable hydrogel microbeads enabling targeted local delivery, immune protection, and controlled release.
Hydrogel microbead encapsulation platform
A platform technology to encapsulate cells, cell clusters, peptides, antibodies, or scaffolds in tunable hydrogel microbeads enabling targeted local delivery, immune protection, and controlled release.
Services
Custom encapsulation development for cell therapies
Collaborative development of tailored hydrogel microbead formulations and encapsulation processes to target delivery, protect cells from immune attack, and tune release profiles.
Contract research and preclinical testing
Preclinical support including surgical induction in animal models and functional testing of encapsulated cell products to assess engraftment and therapeutic effect.
Analytical characterization and assay harmonization
Analytical services to characterize hydrogel carriers and harmonize critical assays across cell therapy products (viability, function, release testing).
Consulting on manufacturing scale-up and COGs reduction
Process and cost optimization consulting, including analysis of cell expansion/differentiation inputs and design choices to improve manufacturability and reduce final product costs.
Custom encapsulation development for cell therapies
Collaborative development of tailored hydrogel microbead formulations and encapsulation processes to target delivery, protect cells from immune attack, and tune release profiles.
Contract research and preclinical testing
Preclinical support including surgical induction in animal models and functional testing of encapsulated cell products to assess engraftment and therapeutic effect.
Analytical characterization and assay harmonization
Analytical services to characterize hydrogel carriers and harmonize critical assays across cell therapy products (viability, function, release testing).
Consulting on manufacturing scale-up and COGs reduction
Process and cost optimization consulting, including analysis of cell expansion/differentiation inputs and design choices to improve manufacturability and reduce final product costs.
Expertise Areas
- Cell therapy delivery system development
- Hydrogel formulation and crosslinking chemistry
- Microencapsulation and microbead manufacturing
- Preclinical evaluation of cell therapies
Key Technologies
- Core-shell hydrogel spherification
- Hydrogel microbeads for cell and biologic encapsulation
- Natural, synthetic, and hybrid hydrogel chemistries (e.g., HA, PEG, PVA)
- Chemical, photo-initiated, ionic, and thermal crosslinking