KLISBio
KLISBio is a clinical-stage regenerative medicine company based in Milan, Italy, dedicated to developing innovative solutions leveraging silk fibroin to promote tissue regeneration. The company focuses on creating versatile, biocompatible implantable products for clinical indications such as nerve repair, vascular diseases, bone defects, and tendon tears. With a strong leadership team and a portfolio of patents, KLISBio aims to revolutionize regenerative medicine through its silk-based technology platform.
Industries
Nr. of Employees
small (1-50)
Products
Silk fibroin nerve conduit (nerve guide)
Absorbable, multilayered silk fibroin nerve conduit combining electrospun inner/outer layers and a textile intermediate layer designed to support peripheral nerve regeneration by providing porosity, mechanical resistance and a controlled resorption profile.
Silk-based vascular graft (development)
Silk fibroin-based grafts intended for peripheral vascular applications; part of the platform pipeline under development.
Silk-based bone graft substitute (development)
Silk fibroin-derived matrices and composites aimed at bone defect repair and grafting applications.
Silk-based rotator cuff / tendon repair implants (development)
Implantable silk fibroin constructs intended to support tendon and rotator cuff repair through scaffold-mediated regeneration.
Silk fibroin nerve conduit (nerve guide)
Absorbable, multilayered silk fibroin nerve conduit combining electrospun inner/outer layers and a textile intermediate layer designed to support peripheral nerve regeneration by providing porosity, mechanical resistance and a controlled resorption profile.
Silk-based vascular graft (development)
Silk fibroin-based grafts intended for peripheral vascular applications; part of the platform pipeline under development.
Silk-based bone graft substitute (development)
Silk fibroin-derived matrices and composites aimed at bone defect repair and grafting applications.
Silk-based rotator cuff / tendon repair implants (development)
Implantable silk fibroin constructs intended to support tendon and rotator cuff repair through scaffold-mediated regeneration.
Services
Clinical collaboration and early-adopter engagement
Partnerships with surgeons and clinical sites to design studies, recruit early adopters and collect clinical feedback for implantable silk-based devices.
Research partnerships and provision of scientific materials
Collaboration with research institutes and provision of materials, scientific literature and laboratory support for translational projects.
Regulatory and clinical development support
Planning and advisory services for regulatory pathways (CE Mark) and design of pivotal clinical trials to support market approval.
Clinical collaboration and early-adopter engagement
Partnerships with surgeons and clinical sites to design studies, recruit early adopters and collect clinical feedback for implantable silk-based devices.
Research partnerships and provision of scientific materials
Collaboration with research institutes and provision of materials, scientific literature and laboratory support for translational projects.
Regulatory and clinical development support
Planning and advisory services for regulatory pathways (CE Mark) and design of pivotal clinical trials to support market approval.
Expertise Areas
- Regenerative medicine
- Peripheral nerve repair
- Implantable scaffold design
- Biomaterials processing (silk fibroin)
Key Technologies
- Silk fibroin biomaterials
- Electrospinning (nanofibers)
- Textile/braided scaffold fabrication
- Core-shell nanofibers