Intravacc


Intravacc, based in the Netherlands within the Utrecht Science Park in Bilthoven, is a globally recognized leader in translational vaccinology. With over 100 years of experience, they serve as an independent Contract Development and Manufacturing Organization (CDMO) in the vaccine industry. Their mission is to bridge discoveries and early-stage clinical trials, mitigating risks and reducing costs in vaccine development.

Industries

biotechnology
health-care
medical

Nr. of Employees

medium (51-250)

Intravacc

Utrecht Science Park, Bilthoven, Netherlands


Patents

Process for producing outer membrane vesicles

US-11542467-B2

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Modified tetra-acylated neisserial LPS

US-11389520-B2

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Modified hexa-acylated neisserial LPS

US-11292808-B2

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Bordetella vaccines comprising LPS with reduced reactogenicity

US-11291713-B2

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Surface display of antigens on Gram-negative outer membrane vesicles

US-11040010-B2

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Surface display of antigens on gram-negative outer membrane vesicles

US-10639280-B2

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Products

Outer membrane vesicle (OMV) vaccine platform

A platform using outer membrane vesicles for antigen presentation and vaccine formulation for infectious disease and oncology indications.

Vero cell–based vaccine production platform

A platform using a Vero GMP cell line for reliable large-scale production of viral vaccines.

Conjugate vaccine development platform

Platform focused on conjugation methods and design for cost-effective conjugate vaccines.

E. coli recombinant protein expression platform

Bacterial expression system platform for rapid and cost-effective production of recombinant proteins used as vaccine antigens.


Services

Contract development and manufacturing services to advance vaccine candidates from discovery to early clinical material supply.

Upstream and downstream process development to enable reproducible, scalable vaccine manufacturing.

Development of analytical assays and methods to characterize vaccine components and support quality control.

GMP-compliant production of clinical- and commercial-grade vaccine material.

Expertise Areas

  • Translational vaccinology and clinical translation
  • Vaccine platform development
  • Bioprocess development and scale-up
  • GMP vaccine manufacturing
  • Show More (3)

Key Technologies

  • Outer membrane vesicles (OMV)
  • Vero cell–based viral vaccine production
  • Conjugation chemistry for conjugate vaccines
  • E. coli recombinant protein expression
  • Show More (3)

News & Updates

Over 100 Years of Experience

Intravacc has over a century of experience in vaccine development.

Global Customer Base

Serves over 50 customers worldwide.

Scientific Publications

Published over 300 scientific articles.

State-of-the-art Facilities

Operates with more than 2000 square meters of advanced facilities.


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