Integrity Bio
Global contract development and manufacturing organization (CDMO) providing integrated discovery, development and GMP manufacturing services for small molecules, generic APIs and biologics. Services include assay development and high-throughput screening, medicinal chemistry, DMPK/bioanalysis, structural biology and protein production, chemical process R&D and scale-up, fermentation/biocatalysis, continuous flow chemistry, and cGMP API and sterile/HPAPI manufacturing across a multi-site global network.
Industries
Nr. of Employees
medium (51-250)
Integrity Bio
Patents
Products
Propanephosphonic acid anhydride reagent supply and process development
Supply and process development program for propanephosphonic acid anhydride reagent at development and commercial scales for coupling and water-management chemistries.
Oxa acids portfolio
Commercial supply of oxo/oxa-type acids in multiple chain lengths and functionalities for pharmaceutical, specialty and materials applications.
Propanephosphonic acid anhydride reagent supply and process development
Supply and process development program for propanephosphonic acid anhydride reagent at development and commercial scales for coupling and water-management chemistries.
Oxa acids portfolio
Commercial supply of oxo/oxa-type acids in multiple chain lengths and functionalities for pharmaceutical, specialty and materials applications.
Services
Turnkey or modular discovery support including assay development, HTS, medicinal chemistry, structural biology and DMPK to progress hits to candidates.
Custom biochemical and cell-based assay development, compound screening, HTS automation and multiparametric imaging-based profiling.
Route design, custom synthesis and cGMP manufacture of APIs and intermediates from discovery to commercial scale including chiral chemistry and complex chemistries.
Route scouting, process optimization, kilo-scale labs, PAT-assisted scale-up and late-phase process understanding and intensification.
Commercial cGMP production of APIs including sterile and aseptic APIs, high-potency compounds and controlled substances across multiple global GMP sites with certified containment options.
End-to-end flow chemistry development from lab-scale photochemical and thermal reactors through pilot and GMP-capable flow systems, including custom reactor design and process transfer to manufacturing.
Turnkey or modular discovery support including assay development, HTS, medicinal chemistry, structural biology and DMPK to progress hits to candidates.
Custom biochemical and cell-based assay development, compound screening, HTS automation and multiparametric imaging-based profiling.
Route design, custom synthesis and cGMP manufacture of APIs and intermediates from discovery to commercial scale including chiral chemistry and complex chemistries.
Route scouting, process optimization, kilo-scale labs, PAT-assisted scale-up and late-phase process understanding and intensification.
Commercial cGMP production of APIs including sterile and aseptic APIs, high-potency compounds and controlled substances across multiple global GMP sites with certified containment options.
End-to-end flow chemistry development from lab-scale photochemical and thermal reactors through pilot and GMP-capable flow systems, including custom reactor design and process transfer to manufacturing.
Expertise Areas
- Small-molecule discovery and medicinal chemistry
- Assay development and high-content phenotypic screening
- DMPK, ADMET and bioanalysis
- Computer-aided drug design and cheminformatics
Key Technologies
- Photochemical and thermal flow reactors
- Jacketed microreactors
- Fixed-bed hydrogenation reactors
- Pilot- and GMP-capable continuous flow systems
News & Updates
Scheduled industry event listing; contact available to arrange meetings regarding APIs, small molecules, biologics, analytical or sterile fill-finish needs.
Scheduled industry event listing; contact available to arrange meetings regarding APIs, small molecules, biologics, analytical or sterile fill-finish needs.