Inflammatory Response Research
Inflammatory Response Research, Inc. (IRR) is a drug development company focused on pharmaceutical products for the treatment of inflammatory disorders and conditions. They are currently developing a safe and effective therapeutic for COVID-19 and a 'First Response' injectable for acute inflammation related to polytrauma and traumatic brain injury, aiming to address unmet medical needs with innovative treatments.
Industries
Nr. of Employees
small (1-50)
Inflammatory Response Research
Santa Barbara, California, United States, North America
Products
Oral combination antihistamine + leukotriene receptor antagonist therapy (developmental)
Oral small-molecule combination therapy developed to modulate multiple inflammatory pathways for acute respiratory inflammatory conditions, evaluated in early clinical studies for safety and effects on pulmonary function.
Injectable 'first response' anti-inflammatory for polytrauma / traumatic brain injury (developmental)
Injectable formulation intended for immediate use in acute trauma and traumatic brain injury to attenuate inflammation and support lung function.
Oral combination antihistamine + leukotriene receptor antagonist therapy (developmental)
Oral small-molecule combination therapy developed to modulate multiple inflammatory pathways for acute respiratory inflammatory conditions, evaluated in early clinical studies for safety and effects on pulmonary function.
Injectable 'first response' anti-inflammatory for polytrauma / traumatic brain injury (developmental)
Injectable formulation intended for immediate use in acute trauma and traumatic brain injury to attenuate inflammation and support lung function.
Services
Clinical development and trial support
Design and conduct of clinical studies including Phase I execution, safety monitoring, and multicenter randomized trial design.
Preclinical pharmacology and formulation services
Preclinical in vitro and in vivo testing, PK/PD profiling, and development of oral and injectable formulations for acute inflammatory indications.
Clinical development and trial support
Design and conduct of clinical studies including Phase I execution, safety monitoring, and multicenter randomized trial design.
Preclinical pharmacology and formulation services
Preclinical in vitro and in vivo testing, PK/PD profiling, and development of oral and injectable formulations for acute inflammatory indications.
Expertise Areas
- Clinical trial management and execution
- Clinical trial design (randomized, placebo-controlled)
- Preclinical pharmacology and translational research
- Anti-inflammatory small-molecule therapeutic development
Key Technologies
- In vitro antiviral assays
- Animal models (ARDS and acute lung injury)
- Pharmacokinetics / PK profiling
- Pharmacodynamics and receptor occupancy analysis