Immunotrex Biologics
Immunotrex is an R&D-focused company that develops experimental technologies for biomedical research and related applications. Its publicly described work includes engineered peptides that neutralize bacterial endotoxin, PEG-based nanoparticle transport and encapsulation systems, methods for chemo-enzymatic nanoparticle synthesis, RNAi delivery approaches using viral/phage capsids, development of synthetic red blood cell/plasma substitutes, cryptographic data-security tools for biomedical data, and a photobiological hydrogen/biofuel production process. The company licenses technologies and seeks collaboration partners for development and scale-up.
Industries
Nr. of Employees
small (1-50)
Immunotrex Biologics
Products
LPS-neutralizing engineered peptide candidates
Small engineered peptides that bind LPS and inhibit LPS:CD14 interactions; multiple structural classes described for potential anti-sepsis therapeutics.
Water-based PEG polymer nanoparticle delivery system
Inert PEG copolymer nanoparticles (50–80 nm) designed for transport and delivery of diverse molecular cargos; described as biologically inactive and amenable to tailored material design.
RNAi delivery system using capsid-based targeting
Method for delivering hairpin RNAi oligomers inside capsid structures with targeting 'arms' intended to direct delivery to cancer cells.
PEG-based synthetic red blood cell and plasma substitute formulations
PEG nanoparticle formulations designed to encapsulate hemoglobin for use as artificial red blood cell substitutes with prolonged circulation potential.
Solid-phase high-yield photobiological hydrogen and biofuel process
Solid-phase photobiological process reported to increase yields of hydrogen and biofuel components relative to conventional photobiological methods; described as being scaled from pilot production.
Biomedical data-security cryptographic tools
Elliptic-curve–based cryptographic solutions for securing scientific and personal data, enabling operations on encrypted data while preserving privacy for analytics and secure sharing.
LPS-neutralizing engineered peptide candidates
Small engineered peptides that bind LPS and inhibit LPS:CD14 interactions; multiple structural classes described for potential anti-sepsis therapeutics.
Water-based PEG polymer nanoparticle delivery system
Inert PEG copolymer nanoparticles (50–80 nm) designed for transport and delivery of diverse molecular cargos; described as biologically inactive and amenable to tailored material design.
RNAi delivery system using capsid-based targeting
Method for delivering hairpin RNAi oligomers inside capsid structures with targeting 'arms' intended to direct delivery to cancer cells.
PEG-based synthetic red blood cell and plasma substitute formulations
PEG nanoparticle formulations designed to encapsulate hemoglobin for use as artificial red blood cell substitutes with prolonged circulation potential.
Solid-phase high-yield photobiological hydrogen and biofuel process
Solid-phase photobiological process reported to increase yields of hydrogen and biofuel components relative to conventional photobiological methods; described as being scaled from pilot production.
Biomedical data-security cryptographic tools
Elliptic-curve–based cryptographic solutions for securing scientific and personal data, enabling operations on encrypted data while preserving privacy for analytics and secure sharing.
Services
Licensing of developed technologies to third parties and collaboration on development and scale-up for biotechnology and life-sciences applications.
Licensing of developed technologies to third parties and collaboration on development and scale-up for biotechnology and life-sciences applications.
Expertise Areas
- Peptide therapeutics for endotoxin neutralization
- Nanoparticle drug transport and delivery
- Chemo-enzymatic nanoparticle synthesis
- RNAi delivery and targeted nucleic-acid therapeutics
Key Technologies
- PEG-based nanoparticles (50–80 nm)
- Chemo-enzymatic nanoparticle synthesis
- LPS-binding/host-defense peptides
- RNA interference (RNAi)