Immundnz


Immundnz is a specialized immunology CRO that offers customized in vitro immunology research services for drug discovery, focusing on immune mechanisms, protein biology, and experimental design. They develop tailored assays and models to study immune interactions, immune risk assessment, and systemic diseases, supporting therapeutic development in oncology, infectious diseases, and autoimmune conditions. Their mission is to help researchers make better decisions in drug development through advanced immunological solutions and translational data.

Industries

biotechnology
health-care

Nr. of Employees

small (1-50)

Immundnz

Chester, Cheshire, United Kingdom, Europe


Products

Immune Modelling & Experimental Design

Designs and develops experimental models to study immune interactions, including pre-clinical and non-clinical models (in vitro, ex vivo, and in vivo).

Immune Risk Assessment

Provides critical information on immune drug safety in the pre-clinical phase, including assays to predict immune-mediated adverse drug reactions.

Tissue Damage & Cytotoxicity

Offers assays to assess drug-induced tissue damage and cytotoxicity using in vitro cell systems representing human tissues.

Immuno-Oncology & Immunotoxicity

Develops models and assays to study the immunobiology of cancer and predict the immunotoxicological response of drugs.

Inflammation & Systemic Diseases

Designs models to study inflammatory and systemic diseases, including assays for phagocytosis, macrophage polarization, and T-helper pathways.

Vaccines, Drug Delivery & Transfection

Provides assays to evaluate the safety and efficacy of vaccines, drug delivery systems, and transfection methods.


Services

Consultancy and laboratory support to design experimental models and study routes (cell-function, cell-based, therapeutic-area) to test immune responses and signalling relevant to drug discovery and preclinical research.

Assessment services to evaluate immune safety concerns and immunogenicity potential of vaccine components, biologics or other therapeutic molecules.

Provision of a catalogue of standard assays (e.g., macrophage polarisation, ADCP/ADCC, CRA, MLR, dendritic cell maturation, T cell assays, viability and apoptosis assays) and development of customised assays based on client needs.

Expertise Areas

  • Preclinical immunology and translational human assays
  • Assay development and customisation for immunology
  • Immunotoxicity and immune risk assessment
  • Immuno-oncology assay development
  • Show More (4)

Key Technologies

  • Flow cytometry (including intracellular staining)
  • ELISA and multiplex cytokine assays
  • Cell-based co-culture assays (MLR, PBMC-based)
  • T cell differentiation and proliferation assays (including Th17 models)
  • Show More (5)

News & Updates

Learn more about immunotoxicity and immune-mediated toxicity and their importance in drug discovery.

Application of flow cytometry in preclinical drug discovery and its importance in immunology research.

Overview of immunology research approaches and their significance in drug development.

Discussion on the complex immune pathways involved in drug discovery and how to approach them.


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