IMAX Discovery
AXXSense is the business platform of Axxam S.p.A., dedicated to the discovery and characterization of novel taste, olfactory, and somatosensory modulating ingredients. It supports industries such as food, beverage, pet food, cosmetics, and perfumes through state-of-the-art technology platforms, deep expertise, and natural and synthetic ingredient collections. The company aims to innovate in flavor and fragrance development, providing tailored solutions from target identification to product development.
Industries
Nr. of Employees
medium (51-250)
IMAX Discovery
Konstanz, Baden-Wurttemberg, Germany, Europe
Products
Pure natural compound library (NatPure approx. 15,000 compounds)
A curated collection of ~15,000 pure natural compounds derived from plant and microbial sources, chemically characterized and supplied as HTS-ready DMSO plates.
Purified fractions library (PreFrac ~63,000 samples)
Library of ~63,000 purified fractions derived from microbial extracts (3–6 compounds per fraction), pre-plated for HTS workflows.
Pre-purified extracts library (Advanced Extracts ~21,200 samples)
Collection of ~21,200 pre-purified extracts from bacterial, fungal, plant and edible sources, available in 96- or 384-well plates for screening.
Microbial strain repository (~40,000 strains)
Repository of ~40,000 distinct bacterial and fungal strains with metadata and links to identified producer metabolites for screening and strain selection.
Synthetic diversity screening collection (~349,000 compounds)
A large synthetic compound collection selected for novelty and chemical diversity to complement natural-product screening in discovery campaigns.
Pure natural compound library (NatPure approx. 15,000 compounds)
A curated collection of ~15,000 pure natural compounds derived from plant and microbial sources, chemically characterized and supplied as HTS-ready DMSO plates.
Purified fractions library (PreFrac ~63,000 samples)
Library of ~63,000 purified fractions derived from microbial extracts (3–6 compounds per fraction), pre-plated for HTS workflows.
Pre-purified extracts library (Advanced Extracts ~21,200 samples)
Collection of ~21,200 pre-purified extracts from bacterial, fungal, plant and edible sources, available in 96- or 384-well plates for screening.
Microbial strain repository (~40,000 strains)
Repository of ~40,000 distinct bacterial and fungal strains with metadata and links to identified producer metabolites for screening and strain selection.
Synthetic diversity screening collection (~349,000 compounds)
A large synthetic compound collection selected for novelty and chemical diversity to complement natural-product screening in discovery campaigns.
Services
Development and QC of tailored cell-based and biochemical assays optimized for HTS and downstream profiling.
Automated HTS campaigns using multiple detection technologies to identify bioactive compounds from natural and synthetic libraries.
Focused profiling of selected compounds across diverse targets with secondary assays and data analysis to qualify hits for progression.
Image-based phenotypic assays with multiplexing for mechanism-of-action studies and validation of cellular phenotypes.
Ion-channel functional testing using manual and automated patch-clamp to support assay development and compound characterization.
Provision of natural-product and synthetic compound collections and access to historical bioprofiling data to accelerate discovery.
Development and QC of tailored cell-based and biochemical assays optimized for HTS and downstream profiling.
Automated HTS campaigns using multiple detection technologies to identify bioactive compounds from natural and synthetic libraries.
Focused profiling of selected compounds across diverse targets with secondary assays and data analysis to qualify hits for progression.
Image-based phenotypic assays with multiplexing for mechanism-of-action studies and validation of cellular phenotypes.
Ion-channel functional testing using manual and automated patch-clamp to support assay development and compound characterization.
Provision of natural-product and synthetic compound collections and access to historical bioprofiling data to accelerate discovery.
Expertise Areas
- Taste and olfactory receptor screening and ligand identification
- Natural product library curation and bioprospecting
- High-throughput screening (HTS) campaigns
- Assay development for cell-based and biochemical targets
Key Technologies
- Automated high-throughput screening (384-well format)
- High-content imaging and image analysis
- Cell-based functional assays for GPCRs and ion channels
- Biochemical functional assays
News & Updates
Partnership involving joint research projects and development of business opportunities leveraging each organization’s technologies.
Webinar discussing ectopic olfactory and taste receptors as potential drug targets.
Webinar describing current trends in natural product R&D and AXXSense’s positioning.
Webinar on the applications of olfactory receptors beyond the nose.
Webinar on using bioprofiling for natural product bioactive compound identification.
Webinar on GPCRs’ role in taste and smell perception.
Partnership involving joint research projects and development of business opportunities leveraging each organization’s technologies.
Webinar discussing ectopic olfactory and taste receptors as potential drug targets.
Webinar describing current trends in natural product R&D and AXXSense’s positioning.
Webinar on the applications of olfactory receptors beyond the nose.
Webinar on using bioprofiling for natural product bioactive compound identification.
Webinar on GPCRs’ role in taste and smell perception.