HTCR-Services


HTCR-Services GmbH, founded in 2002 as a spin-off from the University of Regensburg, specializes in providing human tissue-based products and services for medical research and drug development across Europe. With a network of hospitals and surgeons, they offer a broad range of diseased or normal tissues, human primary cells, and biospecimens to accelerate disease marker discovery, molecular diagnostics, target validation, and drug development. Their mission is to facilitate translational medicine by supplying high-quality human biospecimens and primary cells, supporting pre-clinical R&D, biobanking, and research with organoids and biomarkers.

Industries

Analytics
Biotechnology
Clinical Trials
Medical
Biotechnology Research

Nr. of Employees

small (1-50)


Products

Fresh and cryopreserved primary human hepatocytes

Freshly-isolated or cryopreserved primary human hepatocytes prepared for research use in studies of drug metabolism, transport and hepatotoxicity.

Non-parenchymal liver cells and other primary cell types

Isolated primary non-parenchymal liver cells (stellate, Kupffer, sinusoidal endothelial) and other primary cells such as proximal tubule kidney cells and PBMCs.

Processed tissue products (FFPE, cryoblocks, sections)

Preserved tissue products including FFPE blocks, cryoblocks, shock-frozen or RNAlater-preserved samples and prepared sections suitable for histology and molecular assays.

Extracted nucleic acids and proteins from human samples

Prepared molecular extracts such as RNA, cDNA and protein isolates derived from tissue or cell samples for downstream analyses.

Human Hepatocytes For Research

Primary human hepatocytes purified with optimized methods that result in high cell viability and purity, available for overnight shipping for researchers in the EU or Switzerland.

Human tissue procurement and cell isolation services

Collection of matching fresh human tissues and blood from surgical operations for pre-clinical R&D programs, alongside the isolation of functional cell populations from biospecimens.

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Services

Access to and distribution of retrospective tissue collections and archived biospecimens for research use.

Prospective collection of fresh tissues and matching biological fluids from surgical procedures according to study specifications and ethical approvals.

Isolation, purification and provision of freshly-isolated or cryopreserved primary human cells (including hepatocytes and various non-parenchymal cells).

Processing of tissues into formats such as FFPE blocks, cryoblocks and RNAlater-preserved samples; sectioning and histological preparation.

Testing of candidate compounds on human-derived cells and tissues to assess metabolism, transport, toxicity and pharmacology in pre-clinical stages.

Collaborative biomarker discovery and validation projects, including partnerships with external laboratories.

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Expertise Areas

  • Biobanking and specimen repository management
  • Primary human cell isolation and supply (hepatocytes, non-parenchymal cells, PBMCs)
  • Tissue processing and preservation (FFPE, cryopreservation, RNAlater)
  • Pre-clinical ex-vivo drug screening and ADME/toxicology support
  • Show More (4)

Key Technologies

  • Cryopreservation and cold-chain shipment
  • Formalin-fixed paraffin-embedded (FFPE) processing
  • Tissue cryosectioning and histological staining
  • RNA extraction and cDNA synthesis
  • Show More (5)

News & Updates

Research with human tissue and cells has undergone a major transformation, emphasizing disease understanding, diagnostics, and personalized therapy. The symposium will feature experts from clinics, research, and industry discussing biobanking, personalized medicine, organoids, and ethical aspects.


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