Cureline
Cureline is a global translational and precision medicine CRO providing human biospecimen biobanking and laboratory services for accelerated drug research and development, diagnostics, and scientific studies. Established in 2003 in the San Francisco Bay area, Cureline collaborates with over 150 clinical partners across 20 countries, supporting thousands of projects and participating in major NIH consortiums like TCGA and CPTAC. The company offers a wide range of biospecimen acquisition, management, and analytical services, including custom protocols, histopathology, molecular testing, digital pathology, biobanking of various tissue and blood samples for multiple therapeutic areas. Cureline also specializes in hematology specimen collection, including blood and bone marrow from patients with hematologic malignancies, and provides comprehensive histology and digital pathology services.
Industries
Nr. of Employees
small (1-50)
Cureline
Products
Predefined biospecimen cohort sets
Curated specimen cohorts combining matched tissues, biofluids and viable cells with de-identified clinical metadata for biomarker discovery and assay validation.
Fresh-frozen tissue specimens
Snap-frozen tissue samples prepared under standardized SOPs for RNA, DNA and protein analysis, supplied in cryovials/cassettes.
FFPE blocks and histology slides
Research-grade FFPE blocks prepared to IHC-grade standards with associated slides from a wide range of normal and diseased tissues.
Hematologic malignancy specimen sets
Predefined and custom collections specific to hematologic cancers containing cancer PBMCs (viable and frozen), marker-specific cells, bone marrow aspirates, trephine biopsy FFPE/frozen blocks and matching serum/plasma with clinical annotations.
Predefined biospecimen cohort sets
Curated specimen cohorts combining matched tissues, biofluids and viable cells with de-identified clinical metadata for biomarker discovery and assay validation.
Fresh-frozen tissue specimens
Snap-frozen tissue samples prepared under standardized SOPs for RNA, DNA and protein analysis, supplied in cryovials/cassettes.
FFPE blocks and histology slides
Research-grade FFPE blocks prepared to IHC-grade standards with associated slides from a wide range of normal and diseased tissues.
Hematologic malignancy specimen sets
Predefined and custom collections specific to hematologic cancers containing cancer PBMCs (viable and frozen), marker-specific cells, bone marrow aspirates, trephine biopsy FFPE/frozen blocks and matching serum/plasma with clinical annotations.
Services
Centralized storage, annotation, QC, and distribution of FFPE, fresh-frozen tissues, blood and bone marrow specimens; inventory management and sample retrieval.
Design and implementation of study-specific specimen collection and processing protocols, IRB/ethical committee alignment, CRF design and logistics planning.
High-definition scanning at research magnifications, multi-channel fluorescence capture, image format conversion and temporary cloud storage for downloads and transfers.
Preparation and provision of biospecimens optimized for genomic and proteomic assays and participation in large-scale proteogenomics initiatives.
End-to-end management of clinical biospecimens for trials including site selection/training, kit design, monitoring, specimen collection supervision and chain-of-custody procedures.
Full-service histology including tissue grossing, paraffin and OCT embedding, slide preparation, IHC and FISH assays, custom IHC development and pathology reporting by board-certified pathologists.
Centralized storage, annotation, QC, and distribution of FFPE, fresh-frozen tissues, blood and bone marrow specimens; inventory management and sample retrieval.
Design and implementation of study-specific specimen collection and processing protocols, IRB/ethical committee alignment, CRF design and logistics planning.
High-definition scanning at research magnifications, multi-channel fluorescence capture, image format conversion and temporary cloud storage for downloads and transfers.
Preparation and provision of biospecimens optimized for genomic and proteomic assays and participation in large-scale proteogenomics initiatives.
End-to-end management of clinical biospecimens for trials including site selection/training, kit design, monitoring, specimen collection supervision and chain-of-custody procedures.
Full-service histology including tissue grossing, paraffin and OCT embedding, slide preparation, IHC and FISH assays, custom IHC development and pathology reporting by board-certified pathologists.
Expertise Areas
- Clinical trial specimen management
- Biobanking and biorepository operations
- Tissue processing and histology (FFPE and frozen)
- Blood and bone marrow sample processing
Key Technologies
- Whole-slide imaging (brightfield and fluorescence)
- High-definition slide scanners
- Cryopreservation and controlled-rate freezing
- Snap-freezing in liquid nitrogen
News & Updates
Explore the key differences between fresh tumor tissues and DTCs in immunology research, including applications, benefits, and limitations.
An article discussing the importance of quality control in human biospecimen repositories.
Celebrating two decades of leadership in biobanking and translational research.
Learn about the role CROs play in advancing immuno-oncology and the challenges faced.
Announcement of a strategic partnership to offer end-to-end solutions for medical innovation.
A comprehensive guide on human specimen types, formats, and applications.
Explore the key differences between fresh tumor tissues and DTCs in immunology research, including applications, benefits, and limitations.
An article discussing the importance of quality control in human biospecimen repositories.
Celebrating two decades of leadership in biobanking and translational research.
Learn about the role CROs play in advancing immuno-oncology and the challenges faced.
Announcement of a strategic partnership to offer end-to-end solutions for medical innovation.
A comprehensive guide on human specimen types, formats, and applications.