Echelon Biosciences, Inc
Echelon Biosciences is dedicated to developing research reagents and assays that lead to diagnostics and drug treatments for diseases, with a focus on Lipid and Cell Signaling. They aim to drive scientific progress by providing high-quality solutions, collaborating with scientists, and supporting complex research challenges.
Industries
Nr. of Employees
small (1-50)
Echelon Biosciences, Inc
Salt Lake City, Utah, United States, North America
Products
Research-grade cardiolipin (16:0) reagent
Purified cardiolipin (16:0) supplied for research use with specified purity, storage conditions and technical data sheet.
Lyso-phosphatidylethanol (16:0 LysoPEth) standard
Research-grade LysoPEth (16:0) supplied as a biomarker standard for LC-MS workflows with technical data sheet and storage instructions.
LysoPE (16:0 LPE) research lipid
Purified lysophosphatidylethanolamine (16:0) for use in cell signaling and lipid mediator studies with associated technical documentation.
Catalog of ionizable and cationic lipids
Catalog supply of multiple research ionizable/cationic lipids commonly used for LNP formulation and research screening of nucleic-acid delivery.
Purified Anti-Phosphatidylethanol (PEth) antibody
Affinity-purified antibody reactive primarily with phosphatidylethanol, validated for ELISA and fluorescence microscopy, supplied with storage and handling guidance.
Tetramethylrhodamine-conjugated anti-PI(4,5)P2 antibody (TMR)
Monoclonal antibody against PI(4,5)P2 conjugated to a tetramethylrhodamine fluorophore for immunofluorescence and ELISA applications, supplied at defined concentration ranges.
Research-grade cardiolipin (16:0) reagent
Purified cardiolipin (16:0) supplied for research use with specified purity, storage conditions and technical data sheet.
Lyso-phosphatidylethanol (16:0 LysoPEth) standard
Research-grade LysoPEth (16:0) supplied as a biomarker standard for LC-MS workflows with technical data sheet and storage instructions.
LysoPE (16:0 LPE) research lipid
Purified lysophosphatidylethanolamine (16:0) for use in cell signaling and lipid mediator studies with associated technical documentation.
Catalog of ionizable and cationic lipids
Catalog supply of multiple research ionizable/cationic lipids commonly used for LNP formulation and research screening of nucleic-acid delivery.
Purified Anti-Phosphatidylethanol (PEth) antibody
Affinity-purified antibody reactive primarily with phosphatidylethanol, validated for ELISA and fluorescence microscopy, supplied with storage and handling guidance.
Tetramethylrhodamine-conjugated anti-PI(4,5)P2 antibody (TMR)
Monoclonal antibody against PI(4,5)P2 conjugated to a tetramethylrhodamine fluorophore for immunofluorescence and ELISA applications, supplied at defined concentration ranges.
Services
Lipid nanoparticle (LNP) formulation services
Formulation and optimization of LNPs including ionizable lipid selection, microfluidic mixing, encapsulation efficiency testing, and pre-screening in cell culture.
Assay services (contract execution of validated assays)
Turnkey execution of validated research-use assays with sample receipt and handling, data analysis and QA with certificate of analysis.
Custom chemical synthesis and scale-up
Custom synthesis of complex lipids, phospholipids, sphingolipids, small heterocycles, peptides and isotope-labeled standards with purification and analytical support; scale-up from milligram to multigram quantities.
mRNA synthesis (In Vitro Transcription) services
In vitro transcription production of mRNA cargos with co-transcriptional capping, optional modified nucleotides and downstream purification tailored for formulation projects.
Nanobody and antibody production services
Production of nanobodies and antibodies, including affinity purification, conjugation to labels, and technical support for integrating reagents into assays.
Custom assay development and microplate/bead coating
Design and development of custom assays, custom microplate and bead coatings, and bespoke bioconjugation to support novel assay formats or reagent capture needs.
Lipid nanoparticle (LNP) formulation services
Formulation and optimization of LNPs including ionizable lipid selection, microfluidic mixing, encapsulation efficiency testing, and pre-screening in cell culture.
Assay services (contract execution of validated assays)
Turnkey execution of validated research-use assays with sample receipt and handling, data analysis and QA with certificate of analysis.
Custom chemical synthesis and scale-up
Custom synthesis of complex lipids, phospholipids, sphingolipids, small heterocycles, peptides and isotope-labeled standards with purification and analytical support; scale-up from milligram to multigram quantities.
mRNA synthesis (In Vitro Transcription) services
In vitro transcription production of mRNA cargos with co-transcriptional capping, optional modified nucleotides and downstream purification tailored for formulation projects.
Nanobody and antibody production services
Production of nanobodies and antibodies, including affinity purification, conjugation to labels, and technical support for integrating reagents into assays.
Custom assay development and microplate/bead coating
Design and development of custom assays, custom microplate and bead coatings, and bespoke bioconjugation to support novel assay formats or reagent capture needs.
Expertise Areas
- Lipid chemistry and specialty lipid synthesis
- Lipid nanoparticle formulation and screening
- mRNA in vitro transcription for research applications
- Assay development and contract assay execution (ELISA, AlphaScreen)
Key Technologies
- Ionizable and cationic lipid synthesis
- Lipid nanoparticles (LNPs)
- In vitro transcription (IVT) for mRNA
- Microfluidic mixing for LNP formulation