First Choice Bio


First Choice Bio is dedicated to providing diverse primary cell samples and related research services to biotech, life science, pharmaceutical, academic, and governmental research institutions worldwide. They focus on delivering fresh, high-quality samples within 24 hours and offer high-value laboratory services to enhance research reproducibility and translation into clinical phases.

Industries

biotechnology
life-science
product-research

Nr. of Employees

small (1-50)

First Choice Bio

Benicia, California, United States, North America


Products

Normal human donor samples (blood, plasma, serum, leukopaks, PBMCs, isolated cells, bone marrow, cord blood)

Preclinical research-grade normal donor biological materials available in various formats (fresh and frozen), with optional expanded biomarker screening upon request.

Diseased human donor sample categories (autoimmune, cancer, viral infections)

Preclinical research-grade diseased human donor samples covering autoimmune disorders, various cancers and viral infection disease states available upon request.

Cancer PBMCs (cryopreserved)

Peripheral blood mononuclear cells isolated from cancer patients, purified by density gradient centrifugation and cryopreserved in cryopreservation media; supplied frozen. Donors tested negative for Hepatitis B, Hepatitis C and HIV 1 & 2; IRB consent indicated. Typical vial size: 1 million cells/vial.

Cancer BM-MNCs (cryopreserved)

Bone marrow mononuclear cells isolated from cancer patients (example: multiple myeloma), purified via density gradient centrifugation and provided in cryopreserved frozen format. Donors tested negative for specified infectious agents and IRB consent indicated. Typical vial size: 1 million cells/vial.

Cancer single-donor plasma

Whole-blood-derived single-donor plasma processed by centrifugation and frozen immediately after processing. Donors tested negative for Hepatitis B, Hepatitis C and HIV 1 & 2; IRB consent indicated. Typical vial size: 1 ml per vial.

Non-human primate primary cells

Primary cell products derived from non-human primates (examples include cynomolgus and rhesus) available for preclinical research.


Services

Multiparametric flow cytometry phenotyping using standard and extended leukemia/lymphoma panels and custom panels for sample characterization and Certificate of Analysis generation.

NGS-based molecular assays including targeted gene panels, fusion and MSI detection, whole-exome/transcriptome options and ctDNA/ctRNA analysis for sample characterization.

Screening for over 150 biomarkers (molecular, cellular and infectious) with generation of a Certificate of Analysis to document sample phenotype and biomarker status prior to shipment.

Dedicated in-house courier logistics for rapid global sample delivery with concierge-style handling and cold-chain management.

Search and sourcing of specific sample types through a network of collaborating organizations and custom quote handling for unavailable items.

Expertise Areas

  • Primary cell sourcing and distribution
  • Cryopreservation and biobanking
  • Immunophenotyping by flow cytometry
  • Next-generation sequencing and molecular profiling
  • Show More (4)

Key Technologies

  • Next-generation sequencing (NGS)
  • Multiplex PCR-to-NGS workflows
  • Flow cytometry (standard and extended panels)
  • Density-gradient centrifugation (Ficoll) for PBMC/BM-MNC isolation
  • Show More (4)

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