BioIVT
Provider of ethically sourced, IRB-approved human and animal biospecimens and laboratory services to support preclinical and translational research. Maintains a large pathology-reviewed tissue and biofluid repository (>200,000 items) in multiple preservation formats (fresh frozen, FFPE, OCT, double-spun plasma) and offers custom collection programs, cryopreserved primary cells, subcellular fractions and recombinant enzymes. Provides in vitro ADME/PK and bioanalysis testing, transporter and enzyme assay panels, consulting for ADME/DDI and regulatory strategy, microphysiological and ex vivo model systems, and a secure online portal for inventory access, ordering and enterprise procurement integrations.
Industries
Nr. of Employees
large (251-1000)
Products
Characterized Human Biospecimens (tissues, biofluids, cells)
IRB-approved human tissues, blood-derived biofluids, other biofluids, primary cells, extracellular vesicles and molecular derivatives provided in multiple preservation formats with associated clinical and donor metadata. Repository includes pathology-reviewed specimens and double-spun plasma; samples are barcoded and documented for traceability.
Custom Biofluids, Cell Products and Reagents
Configurable biofluid collections, custom cell isolations, recombinant enzymes, kits and controls produced to specification for assay development, validation cohorts and method development.
Characterized Human Biospecimens (tissues, biofluids, cells)
IRB-approved human tissues, blood-derived biofluids, other biofluids, primary cells, extracellular vesicles and molecular derivatives provided in multiple preservation formats with associated clinical and donor metadata. Repository includes pathology-reviewed specimens and double-spun plasma; samples are barcoded and documented for traceability.
Custom Biofluids, Cell Products and Reagents
Configurable biofluid collections, custom cell isolations, recombinant enzymes, kits and controls produced to specification for assay development, validation cohorts and method development.
Services
ADME and DDI testing including metabolic stability, CYP inhibition/induction, transporter interactions, and metabolite identification.
Expert review of preclinical and clinical data, gap analyses, study design recommendations, technical writing and deliverables for regulatory readiness.
Analytical characterization and QC of biospecimens with donor annotation and documentation to support study reproducibility and regulatory expectations.
Secure online portal providing real-time inventory, pricing, order/quote management, shipment tracking and access to gated resources for registered users; optional enterprise expansions for integrated procurement catalogs.
Custom collections and processing for biofluids, tissues, cells, exosomes, subcellular fractions and molecular products tailored to protocol requirements.
Panels of transporter and enzyme assays for screening and kinetic characterization to evaluate absorption, distribution and metabolic liabilities.
ADME and DDI testing including metabolic stability, CYP inhibition/induction, transporter interactions, and metabolite identification.
Expert review of preclinical and clinical data, gap analyses, study design recommendations, technical writing and deliverables for regulatory readiness.
Analytical characterization and QC of biospecimens with donor annotation and documentation to support study reproducibility and regulatory expectations.
Secure online portal providing real-time inventory, pricing, order/quote management, shipment tracking and access to gated resources for registered users; optional enterprise expansions for integrated procurement catalogs.
Custom collections and processing for biofluids, tissues, cells, exosomes, subcellular fractions and molecular products tailored to protocol requirements.
Panels of transporter and enzyme assays for screening and kinetic characterization to evaluate absorption, distribution and metabolic liabilities.
Expertise Areas
- Human biospecimen procurement and characterization
- Large-scale pathology-reviewed tissue biobanking
- In vitro ADME, DMPK and drug–drug interaction testing
- Transporter and enzyme kinetic assays
Key Technologies
- Pathology-reviewed human tissue processing (FFPE, fresh frozen, OCT)
- Double-spun plasma preparation
- Cryopreserved primary hepatocytes and cryosuspension cells
- Subcellular fractions (microsomes, S9, cytosol, lysosomes)
News & Updates
Exhibit and symposium participation to discuss biospecimen and ADME study needs; symposium on NAMs moderated by a scientific affairs lead.
Participation and presentation on adapting in vitro ADME strategies for protein degraders.
Participation to present biospecimen and in vitro model capabilities for extracellular vesicle research.
Webinar covering metabolic disease models, case studies and use of human biospecimens, hepatocyte systems, S9 fractions and proteomics for comparative metabolism.
Blog reviewing structural features of airway remodeling and in vitro model options (co-culture, ALI, organoids, lung-on-chip, PCLS) to study epithelial–mesenchymal interactions.
Exhibit and symposium participation to discuss biospecimen and ADME study needs; symposium on NAMs moderated by a scientific affairs lead.
Participation and presentation on adapting in vitro ADME strategies for protein degraders.
Participation to present biospecimen and in vitro model capabilities for extracellular vesicle research.
Webinar covering metabolic disease models, case studies and use of human biospecimens, hepatocyte systems, S9 fractions and proteomics for comparative metabolism.
Blog reviewing structural features of airway remodeling and in vitro model options (co-culture, ALI, organoids, lung-on-chip, PCLS) to study epithelial–mesenchymal interactions.